Protein-Protein Interactions, Networks and Pathways - Chagall
Protein-Protein Interactions, Networks and Pathways - Chagall
Protein-Protein Interactions, Networks and Pathways - Chagall
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Domain-Domain <strong>Interactions</strong>• Many PPI predictions are based on identifyinginteracting domain pairs or domain-motifs. (Ref:Deng et al.,2002, Ng et al.,2003, Riley et al., 2005, Sprinzak et al.,2001,Li et al., 2004, Neduva et al., 2005, Wang et al.,2004, Betel et al.,2007)• Based on identifying over representeddomain pairs in interacting proteins orconserved motifs.• To date, only a small number of conservedrecognition motifs have been identified(Scansite, ELM).
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