Loss of Consciousness and Seizure During Normobaric Hypoxia TrainingMoniaga, Natalie C.; Griswold, Cheryl A.Aviation, Space, and Environmental Medicine, Volume 80, Number 5, May 2009 , pp. 485-488(4)ABSTRACTLoss of consciousness is a symptom with a broad differential diagnosis. Distinguishing between syncopeand seizure in a patient with a history of loss of consciousness can be equally difficult as their presentationcan be very similar. We present the case of a naval electronic countermeasures officer who experienced a lossof consciousness while undergoing hypoxia training with the reduced oxygen breathing device (ROBD). Duringthe episode the patient experienced tonic-clonic contractions with subsequent vertebral fractures, resultingin a prolonged grounding period. The patient's work-up focused on ruling out inherent cardiac and neurologicetiologies. After extensive examination and consultation with neurology, the patient was diagnosed with hypoxiainducedseizure, but was not felt to have an underlying seizure disorder. After reviewing his case, the Naval AerospaceMedical Institute felt that this incident represented a physiologic event and not a medical condition inherentto the aviator. It was, therefore, determined that this episode was not considered disqualifying and did not requirea waiver for return to duties involving flight. Our discussion details the appropriate work-up for loss ofconsciousness, examines possible physiologic explanations for this event, and describes aeromedical considerations.The authors include the patient's physiology instructor, one of the primary witnesses for the event, andthe patient's flight surgeon, who was extensively involved in his care.Ventilated Vest and Tolerance for Intermittent Exercise in Hot, Dry ConditionsWith Military ClothingBarwood, Martin J.; Newton, Phillip S.; Tipton, Michael J.Aviation, Space, and Environmental Medicine, Volume 80, Number 4, April 2009 , pp. 353-359(7)ABSTRACTIntroduction: Recent research has focused on developing air-ventilated garments to improve evaporative coolingin military settings. This study assessed a ventilated vest (Vest) in hot (45°C), dry (10% RH) ambient conditionsover 6h of rest and exercise. It was hypothesized that the Vest would lower the thermal strain and increasethe amount of exercise done by subjects. Methods: Eight healthy heat-acclimated men, wearing combat clothing,body armor, and a 19-kg load in webbing walked on a treadmill at 5 km • h−1 at a 2% incline until rectaltemperature (Trec) reached 38.5°C. They then rested until Trec reached 38°C, at which point they recommencedwalking. On one occasion the subjects wore a Vest, blowing ambient air around the torso. On the second occasionsubjects did not wear the vest (NoVest). Exercise/rest ratio, Trec, skin temperature (Tsk), sweat responses,rating of perceived exertion (RPE), and thermal comfort (TC) were measured. Results: Subjects wearing theVest exercised for significantly longer (18%; 11 min/h) as a percentage of total exposure time, stopped exercisesignificantly less often [Mean (SD); NoVest: 3 (2) stops; Vest: 1 (2) stops], and maintained significantly lowerskin temperature under the body armor [Tchest: NoVest 37.55 (0.51)°C; Vest: 35.33 (1.00)°C; Tback: NoVest:36.85 (0.83)°C; Vest: 35.84 (0.88)°C]. The Vest provided 28 W of cooling during exercise and 73 W when atrest as estimated by thermometry. Conclusion: A ventilated vest can provide cooling, and thereby reduce thermalstrain and increase exercise done in dry environmental temperatures up to 45°C, without causing skin irritationand discomfort.58Journal of <strong>Special</strong> <strong>Operations</strong> Medicine Volume 9, Edition 3 / <strong>Summer</strong> 09
CENTRAL RETINAL VEIN OCCLUSION IN AN ARMY RANGER WITHGLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCYLTC Russ S. Kotwal, MC, USA*; CAPT Frank K. Butler, Jr., MC, USN (Ret.)† ;LTC Clinton K. Murray, MC, USA‡;MAJ Guyon J. Hill, MC, USA§; LTC John C. Rayfield, MC, USA; CPT Ethan A. Miles, MC, USA*Previously published in Military Medicine, 174, 5:544, 2009. Permission granted to republish in the JSOM.ABSTRACTGlucose-6-phosphate dehydrogenase (G6PD) deficiency is the most prevalent human enzyme deficiency, affecting anestimated 400 million people worldwide. G6PD deficiency increases erythrocyte vulnerability to oxidative stress and may precipitateepisodes of hemolysis when individuals are exposed to triggering agents. Although central retinal vein occlusion(CRVO) does occur in G6PD-deficient individuals, G6PD-deficient individuals exposed to oxidative stressors have not beenpreviously reported to have an increase in CRVO incidence. This is a case of an Army Ranger who deployed to Afghanistanwith unrecognized G6PD deficiency and was placed on primaquine following his return to the <strong>United</strong> <strong>States</strong> and subsequentlydeveloped CRVO. Primaquine is a well-recognized cause of hemolysis in individuals with G6PD deficiency. Hemolytic anemiamay contribute to thrombosis as a result of increased erythrocyte aggregation and erythrocyte-endothelium interaction.This case underscores the continued need for routine G6PD screening and avoidance of known triggers in G6PD-deficient individuals.INTRODUCTIONGlucose-6-phosphate dehydrogenase (G6PD) deficiencyis the most common human enzyme disorder in theworld, with over 440 genetic variants and more than 400 millionpeople affected worldwide. 1,2,3 G6PD-deficient individualscan develop acute hemolytic anemia and other associatedreactions when exposed to oxidative stressors including infections,toxins, foodstuffs, and medications. According to existingliterature regarding the occurrence of retinal veinocclusions in this population, G6PD-deficient individuals arepostulated to have a significantly lower risk of developing centralretinal vein occlusion (CRVO). 4 However, the literaturedoes not state the risk of CRVO development in a G6PD-deficientindividual with an on-going oxidative stressor. Retinalvein occlusion, which includes branch retinal vein occlusionand CRVO, is the second most common sight-threatening retinalvascular disorder worldwide following diabetic retinopathy.5 This case presents a patient with unrecognized G6PDdeficiency who was placed on primaquine for malaria prophylaxisand subsequently developed a CRVO.CASE REPORTA 35-year-old active duty Army Ranger of Mediterraneandescent presented to his primary care provider with thechief complaint of constant blurred vision in his right eye withassociated symptoms of photophobia and a “seasick” sensationupon awakening one morning. These symptoms continuedto progressively worsen up until the time of hispresentation two weeks later. He denied ocular pain or anyother symptoms at the time of his initial evaluation.The patient’s past medical history was unremarkableexcept for intermittent mild normocytic normochromic ane-mia of unknown origin initially noted on a routine physical examinationfive years earlier. The patient denied any history ofvisual complaints, treatment for ophthalmologic conditions, tobaccouse, drug allergies, and prior medication complications.The patient’s recent medication history consisted ofdoxycycline 100mg daily for malaria chemoprophylaxis, whichhe consumed before, during, and after a three month deploymentto Afghanistan. He also consumed a two-week course ofprimaquine base 15mg daily concomitantly during the last twoweeks of his doxycycline regimen. Both medications werecompleted the month prior to symptom onset. The patientstated that he was compliant with the medication regimens.The physical examination at the time of presentationrevealed a distance visual acuity without correction of 20/200OD and 20/20 OS. His medical record denoted that he had previouslymaintained a visual acuity of 20/20 bilaterally withoutcorrection. The remainder of his physical exam was unremarkableto include stable vital signs with a normal blood pressure.He was referred to an ophthalmologist who confirmed thedecreased vision in the right eye and also noted an afferentpupillary defect, or Marcus Gunn reaction, of the right pupil.Additionally, the right eye fundoscopic examination was remarkablefor dilated, tortuous veins, diffuse four-quadrant intraretinalhemorrhage, and macular edema. (Figure) Theremainder of the ophthalmologic exam was normal to includenoncontact tonometry intraocular pressures of 14mmHg in eacheye and an unremarkable slit lamp examination.The ophthalmologist diagnosed nonischemic CRVO,and the patient was given a two-week course of brimonidine0.2% one drop twice a day, Cosopt (dorzolamide 2% and timolol0.5%) one drop twice a day, latanoprost 0.005% one dropPreviously Published 59
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An 18D deworms a camel during a “
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Field Evaluation and Management of
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TITLE AUTHOR ISBNI Acted from Princ
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TITLE AUTHOR ISBNRats, Lice, & Hist
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TITLE AUTHOR ISBNThe Healer’s Roa
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GENERAL REFERENCESALERTS & THREATSB
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Aviation Medicine Resources: http:/
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LABORATORYClinical Lab Science Reso
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A 11 year old boy whose tibia conti
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Meet Your JSOM StaffEXECUTIVE EDITO
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Special Forces Aidman's PledgeAs a