Read-Across, Grouping and Categories: possibilities and ... - Europa

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Structural Similarity = Basis of Read-Across• The identity of a substance is defined by structures,composition and so-called chemical descriptors.The statement “these chemicals are similar” has nomeaning in the context of REACH.29/02/2012 18
Core of every RA explanation• What makes the source and target structurally similarand how is that related to the endpoint for which adata-gap has to be filled by means of read-across;• What makes the source and target structurallydissimilar and how does that affect the possibilities toread-across29/02/2012 19
Page 11 and 12: Groups and Categories (4)• Read-a
Page 13 and 14: Read-across (1)• Read-across intr
Page 15 and 16: Possible supporting data• Depends
Page 17: Part of the Legal Text:• Adequate
Page 21 and 22: Possible Read-Across “Explanation
Page 23 and 24: Identity of substances• The valid
Page 27: Thank YouKarel de Raatecha.europa.e

Read-Across, Grouping and Categories: possibilities and ... - Europa

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