Read-Across, Grouping and Categories: possibilities and ... - Europa
Read-Across, Grouping and Categories: possibilities and ... - Europa
Read-Across, Grouping and Categories: possibilities and ... - Europa
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Evaluation of <strong>Read</strong>-<strong>Across</strong> Proposals• Depends on the role of the read-across in the REACHregistration dossier; it can be part of a weight of evidence analysis; its purpose can also be to meet an entire information requirement; is it qualitative or quantitative? it can be part of an integrated testing strategy.• Many cases are rejected because essentialinformation is lacking;• Quality of the explanation <strong>and</strong> the supporting dataplay a crucial role in ECHA’s evaluation;• The evaluation is ultimately based on expert judgement;• Uncertainty or lack of quality may be compensated for byextra uncertainty factors <strong>and</strong> thus by lower DNELs.29/02/2012 24
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