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Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

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<strong>Lomb</strong>-<strong>Scargle</strong> Periodogram Experiment:S<strong>in</strong>gle Dom<strong>in</strong>ant FrequencyCos<strong>in</strong>e Curve (N=48)Expression-1.0 0.0 0.5 1.0N = 480 10 20 30 40Expression = Cos<strong>in</strong>e(2pt/24)Time [hours]Normalized Power Spectral Density0 5 10 20<strong>Lomb</strong>-<strong>Scargle</strong> PeriodogramPeriod at Peak = 24 hoursp = 1e-06p = 1e-05p = 1e-04p = 0.001p = 0.01p = 0.050.00 0.05 0.10 0.15 0.20Probability0.0 0.4 0.8Peak Significancep = 3.3e-009 at Peak0.00 0.05 0.10 0.15 0.20Frequency [1/hour]Frequency [1/hour]S<strong>in</strong>gle “peak” <strong>in</strong> periodogram. S<strong>in</strong>gle “valley” <strong>in</strong> significance curve.12

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