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Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

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Bozdech’s Plasmodium dataset:2. Apply <strong>Lomb</strong>-<strong>Scargle</strong> AlgorithmPhase<strong>Periodic</strong> Expression Patterns Phaseopfi17638Time Interval Variabilityi3518_1Time Interval Variability-4 -2 0 20 10 20 30 40-2 -1 0 10 10 20 30 40N = 460 10 20 30 40-1.0 -0.5 0.0 0.5 1.0N = 460 10 20 30 40-1.0 -0.5 0.0 0.5 1.00 5 10 15 20 25<strong>Lomb</strong>-<strong>Scargle</strong> PeriodogramPeriod at Peak = 45.7 hoursp = 1e-06p = 1e-05p = 1e-04p = 0.001p = 0.01p = 0.050.0 0.2 0.4 0.6 0.8 1.0Peak Significancep = 1.19e-008 at Peak0 5 10 15 20 25<strong>Lomb</strong>-<strong>Scargle</strong> PeriodogramPeriod at Peak = 45.7 hoursp = 1e-06p = 1e-05p = 1e-04p = 0.001p = 0.01p = 0.050.0 0.2 0.4 0.6 0.8 1.0Peak Significancep = 1.48e-008 at Peak0.00 0.05 0.10 0.15 0.20 0.00 0.05 0.10 0.15 0.200.00 0.05 0.10 0.15 0.20 0.00 0.05 0.10 0.15 0.20Examples of highly-significant periodic expression profiles.22

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