Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

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Using Lomb-Scargle Periodogramsto Identify Periodic Genes in Somitogenesis• Periodic Patterns in Biology• Simple Periodic Gene Expression Model• Introduction to Lomb-Scargle Periodogram• Data Pipeline• Methodology Validation Study:Bozdech’s Plasmodium dataset• Application to Mary-Lee’s somitogenesis dataset• Conclusions2
Periodic Patterns in BiologyA vertebrate’s body plan: a segmented pattern.Segmentation is established during somitogenesis.Photograph taken at Reptile Gardens, Rapid City, SDwww.reptile-gardens.com3
Page 1: Using Lomb-Scargle Periodogramsto I
Page 6 and 7: What is a Periodogram?• A graph s
Page 8 and 9: Lomb-Scargle PeriodogramExample Usi
Page 10 and 11: Lomb-Scargle PeriodogramExample Usi
Page 12 and 13: Lomb-Scargle Periodogram Experiment
Page 14 and 15: Lomb-Scargle Periodogram Experiment
Page 16 and 17: Lomb-Scargle Experiment:Mixtures: P
Page 18 and 19: Data Pipeline to Apply to Microarra
Page 20 and 21: Bozdech’s Plasmodium dataset:1. A
Page 30 and 31: Bozdech’s Plasmodium dataset:Boze
Page 32 and 33: Mary-Lee’s Somitogenesis DatasetW
Page 34 and 35: Somitogenesis DatasetMary-Lee, Scie
Page 36 and 37: Somitogenesis DatasetDo we care abo
Page 38 and 39: Somitogenesis DatasetPerturbation (
Page 44 and 45: Somitogenesis DatasetWhat periodici
Page 46 and 47: Conclusions• Lomb-Scargle periodo
Page 48: AcknowledgementsPourquie LabOlivier

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