Using Lomb-Scargle Periodograms to Identify Periodic Genes in ...

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Conclusions• Lomb-Scargle periodogram is effective tool toidentify periodic gene expression profiles• Results comparable with Fourier analysis• Lomb-Scargle can help when data are missingor not evenly spaced46
Conclusions• Conclusions should not be drawn using theindividual p-value calculated for each profile. Amultiple comparison procedure False DiscoveryRate (FDR) must be used to control the error rate.• Expression profiles may be more complex thansimple cosine curves• Power spectra of non-sinusoid rhythms may bedifficult to interpret47
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Page 3: Periodic Patterns in BiologyA verte
Page 6 and 7: What is a Periodogram?• A graph s
Page 8 and 9: Lomb-Scargle PeriodogramExample Usi
Page 10 and 11: Lomb-Scargle PeriodogramExample Usi
Page 12 and 13: Lomb-Scargle Periodogram Experiment
Page 14 and 15: Lomb-Scargle Periodogram Experiment
Page 16 and 17: Lomb-Scargle Experiment:Mixtures: P
Page 18 and 19: Data Pipeline to Apply to Microarra
Page 20 and 21: Bozdech’s Plasmodium dataset:1. A
Page 30 and 31: Bozdech’s Plasmodium dataset:Boze
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Page 38 and 39: Somitogenesis DatasetPerturbation (
Page 44 and 45: Somitogenesis DatasetWhat periodici
Page 48: AcknowledgementsPourquie LabOlivier

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