C O N F E R E N C E R E P O RT SBritish Society of <strong>Rehabilitation</strong> Medic<strong>in</strong>e ConferenceConference details: 14-15 June, 2012; Southampton, UK. Reviewed by: Dr John Burn, <strong>Rehabilitation</strong> Consultant, Poole General Hospital.The Major Trauma Centre (MTC) <strong>in</strong>itiativehas thrust rehabilitation <strong>in</strong>to the limelight<strong>and</strong> it was the focus of this year’s meet<strong>in</strong>g.The identification of patients who needspecialist services will be a particular responsibilityof <strong>Rehabilitation</strong> Medic<strong>in</strong>e (RM) specialists.Presentations from both Manchester <strong>and</strong>London described a cultural change wherebyRM specialists were form<strong>in</strong>g an <strong>in</strong>tegral part ofacute trauma teams <strong>and</strong> mov<strong>in</strong>g patientsquickly on to appropriate rehabilitation facilities.To do this well services need to be availableon the acute site <strong>and</strong> RM physicians need toacquire new skills, particularly <strong>in</strong> musculoskeletalconditions. There was extensivediscussion on the requirements for‘<strong>Rehabilitation</strong> Prescription’. Well organisedMTCs are secur<strong>in</strong>g this not only for patientswith an Injury Severity Score (ISS) of > 15 butalso for > 8 (three fractured ribs) thus secur<strong>in</strong>gmore ‘best practice tariffs’. These monies willhave to be <strong>in</strong>vested <strong>in</strong> enhanced services forthis not just to be a paper exercise.The conference brought unfamiliarspecialisms to the BSRM. Mr Michael Fox fromStanmore described surgical approaches tobrachial plexus <strong>in</strong>jury <strong>and</strong> Dr Chris Lowe fromPoole Hospital described cont<strong>in</strong>u<strong>in</strong>g problemsafter Critical Care. Survival is reduced for 15years after ARDS <strong>and</strong> this is determ<strong>in</strong>ed pr<strong>in</strong>cipallyby weakness. This affects almost 50% ofpatients <strong>and</strong>, although not completely understood,is detectable as a reduced 6 m<strong>in</strong>utewalk<strong>in</strong>g distance for at least 5 years afterwards.There are recommendations for early mobilisationbut little support<strong>in</strong>g evidence as yet.Public awareness of rehabilitation has beenenhanced by the work amongst veterans atHeadley Court. Prof Greenberg, visit<strong>in</strong>gprofessor of psychiatry, gave a robust defence ofthe psychological management of Britishservice personnel. Despite, or maybe becauseof, fewer mental health personnel, the rate ofPTSD is significantly less than <strong>in</strong> the US army<strong>and</strong>, although peak<strong>in</strong>g at 6% at 4 years, appearsto decrease subsequently. The <strong>in</strong>cidence ofPTSD is less for the majority of combatants whodescribe their leadership as good or very goodor who have fewer stresses at home. Early (lessthan 4 year) army discharges or reservists aremore at risk. There is no significant <strong>in</strong>crease <strong>in</strong>suicide or imprisonment but rates of alcoholabuse are frighten<strong>in</strong>gly high: up to 25%.Spiritual care was <strong>in</strong>troduced <strong>in</strong>to a BSRMmeet<strong>in</strong>g by Dr Collicut, both a neuropsychologist<strong>and</strong> an Anglican priest. She dist<strong>in</strong>guishedreligion from spirituality by describ<strong>in</strong>g threeaxes of Transcendence, Mean<strong>in</strong>g <strong>and</strong> TheSacred. Traumatised patients face keen questionsof mean<strong>in</strong>g (why me?) but often becauseof cognitive <strong>and</strong> physical problems are less ablespiritually to address them. Spiritual help cannotbe left to faith practitioners but crosses professionalboundaries. She suggested focus<strong>in</strong>g onShalom (wholeness/peace) through support<strong>in</strong>gdignity <strong>and</strong> identity, convey<strong>in</strong>g hope, <strong>and</strong>express<strong>in</strong>g solidarity <strong>and</strong> lov<strong>in</strong>g k<strong>in</strong>dness.The conference f<strong>in</strong>ished with a symposiumon the def<strong>in</strong>itions <strong>and</strong> management of m<strong>in</strong>orbra<strong>in</strong> <strong>in</strong>jury. We were encouraged to movebeyond the dualisms of ‘is it structural oremotional?’, <strong>and</strong> address the comb<strong>in</strong>ed problemsof patients us<strong>in</strong>g a number of treatmentsthat can be practised <strong>in</strong> the cl<strong>in</strong>ic.In all, a broad <strong>and</strong> satisfy<strong>in</strong>g conference thatdemonstrated to visitors <strong>and</strong> members alike the<strong>in</strong>creas<strong>in</strong>g range of the specialty. The nextconference, from 7th – 9th November 2012,willbe hosted by colleagues <strong>in</strong> Belfast <strong>and</strong> will<strong>in</strong>clude presentations on teleneurology, assistivetechnology, transcranial magnetic stimulation<strong>and</strong> the transitional rehabilitation of childrenwith cerebral palsy. lPREVIEW The Fifth Practical Cognition CourseCourse details: 1-2 November, 2012, Newcastle upon Tyne, UK.This very successful course is for consultants<strong>and</strong> tra<strong>in</strong>ees <strong>in</strong> neurology, psychiatry,neuropsychology <strong>and</strong> rehabilitation medic<strong>in</strong>ewho want to develop their practicalexpertise <strong>in</strong> cognitive assessment <strong>and</strong> relatethis to cl<strong>in</strong>ically relevant neuroscience. Therewill be a practical <strong>in</strong>troductory session tocognitive assessment followed by four sessionsof case presentations discuss<strong>in</strong>g the assessment,diagnosis <strong>and</strong> management of commoncognitive syndromes. The course beg<strong>in</strong>s <strong>and</strong>ends with the patient. Case presentations willfeature video material illustrat<strong>in</strong>g disorders thatcl<strong>in</strong>icians may encounter <strong>in</strong> daily practice.Each session will also <strong>in</strong>clude a talk from an<strong>in</strong>vited expert, who will provide a framework forunderst<strong>and</strong><strong>in</strong>g the cl<strong>in</strong>ically relevant neuroscience.The case presentations <strong>and</strong> talks arehighly <strong>in</strong>teractive <strong>and</strong> lively discussion isencouraged.This year’s programme will cover memory,sleep <strong>and</strong> cognition, halluc<strong>in</strong>ations <strong>and</strong> motorfunction <strong>and</strong> cognition. Our highly acclaimedspeakers <strong>in</strong>clude Kirsty Anderson (Newcastle),David Burn (Newcastle), Tom Kelly(Newcastle), Andrew Larner (Liverpool),S<strong>in</strong>éad Mullally (UCL) <strong>and</strong> Peter Woodruff(Sheffield). The course is organised by neurologistsTim Griffiths (Newcastle) <strong>and</strong> Chris Butler(Oxford), sponsored by the Guarantors of Bra<strong>in</strong><strong>and</strong> will be accredited for CME po<strong>in</strong>ts.The course will be held <strong>in</strong> the Beehiveconference centre on the ma<strong>in</strong> campus ofNewcastle University with<strong>in</strong> the city. The registrationfee <strong>in</strong>cludes a superb d<strong>in</strong>ner on the firsteven<strong>in</strong>g at the Quayside <strong>in</strong> Newcastle.The Practical Cognition course has receivedhighly enthusiastic feedback <strong>in</strong> previous years.Participants have enjoyed the practicalapproach to an area of cl<strong>in</strong>ical work that isextremely important but often neglected <strong>in</strong> postgraduateeducation. Here are l<strong>in</strong>ks to reviews oflast year’s course by a tra<strong>in</strong>ee psychiatrist[http://careers.bmj.com/careers/advice/view-article.html?id=20006682] <strong>and</strong> consultantneurologist [http://www.acnr.co.uk/contents11-6.htm].Book<strong>in</strong>gs can be made onl<strong>in</strong>e (www.practicalcognition.com)or by telephon<strong>in</strong>g LauraPereira on 0191 222 8320. Places are limited <strong>and</strong>should be reserved early. l32 > ACNR > VOLUME 12 NUMBER 4 > SEPTEMBER/OCTOBER 2012
C O N F E R E N C E R E P O RT SThe 10th European Congress of NeuropathologyConference details: 6-9 June, 2012, Ed<strong>in</strong>burgh, Scotl<strong>and</strong>. Reviewed by: Dr Valerie Critcher, Specialist Registrar <strong>in</strong> Neuropathology at the Royal Hallamshire Hospital,Sheffield, UK.An <strong>in</strong>vitation from the European Confederation ofNeuropathological Societies (Euro-CNS) <strong>and</strong> the BritishNeuropathological Society drew almost 400 participants fromacross the globe to the Ed<strong>in</strong>burgh International Conference Centre forthis Neuropathology Congress. The meet<strong>in</strong>g was preceded by the Euro-CNS tra<strong>in</strong><strong>in</strong>g course on Leukoencephalopathies.Plenary LecturesThe programme <strong>in</strong>cluded plenary lectures by eight dist<strong>in</strong>guishedspeakers work<strong>in</strong>g at the forefront of neuroscience research <strong>and</strong> its applicationto improvements <strong>in</strong> diagnosis <strong>and</strong> treatment. In his talk on themolecular pathology of CNS tumours, Professor David Louis focused ondevelopments <strong>in</strong> this rapidly exp<strong>and</strong><strong>in</strong>g field that have been translated<strong>in</strong>to valuable diagnostic <strong>and</strong> prognostic tools. An example was the use ofMGMT promoter methylation to help dist<strong>in</strong>guish glioblastoma recurrencefrom pseudoprogression dur<strong>in</strong>g temozolomide therapy. Professor JohnHardy discussed how advances <strong>in</strong> sequenc<strong>in</strong>g <strong>and</strong> DNA chip technologyare be<strong>in</strong>g used to identify different types of genetic risk for neurodegenerativediseases, thereby <strong>in</strong>creas<strong>in</strong>g underst<strong>and</strong><strong>in</strong>g of the aetiologies.Professor Richard Gilbertson described his laboratory’s cross-speciesgenomics approach to the subgroup<strong>in</strong>g of CNS tumours. This is help<strong>in</strong>gto expla<strong>in</strong> why tumours of similar histopathological appearance mayshow very different biological behaviours. For example, ependymomasaris<strong>in</strong>g <strong>in</strong> the forebra<strong>in</strong>, h<strong>in</strong>dbra<strong>in</strong> <strong>and</strong> sp<strong>in</strong>al cord have dist<strong>in</strong>ct molecularprofiles, reflect<strong>in</strong>g their different stem cell type orig<strong>in</strong>s. Professor WilliamBrown illustrated his techniques of creat<strong>in</strong>g three dimensional views ofvascular networks to <strong>in</strong>vestigate the vascular changes <strong>in</strong> deep whitematter <strong>in</strong> age<strong>in</strong>g, neurodegeneration <strong>and</strong> dementia. The <strong>in</strong>creas<strong>in</strong>gcomplexity <strong>and</strong> diversity of prion diseases were discussed by ProfessorPierluigi Gambetti. He talked about the identification <strong>and</strong> characterisationof novel forms such as variably protease-sensitive prionopathy whichis suggested to represent a sporadic form of Gerstmann-Sträussler-Sche<strong>in</strong>ker disease. Professor Ingmar Blümcke described how the surveyof over 5,000 surgical epilepsy specimens collected at the EuropeanEpilepsy Bra<strong>in</strong> Bank has enabled correlation between histopathology,preoperative imag<strong>in</strong>g <strong>and</strong> cl<strong>in</strong>ical response to surgery, which <strong>in</strong> turn islead<strong>in</strong>g to more specifically tailored resection strategies. Developments<strong>in</strong> underst<strong>and</strong><strong>in</strong>g the pathogenesis of lysosomal diseases were expla<strong>in</strong>edby Professor Steven Walkley. He showed that the complex role of lysosomeswith<strong>in</strong> a major metabolic regulatory network <strong>in</strong>dicates that bra<strong>in</strong>dysfunction <strong>in</strong> lysosomal diseases is not simply the consequence ofabnormal storage of non-degraded materials. In the f<strong>in</strong>al lecture to theCongress, Professor Rob<strong>in</strong> Frankl<strong>in</strong> described the work <strong>in</strong> his laboratoryon the biology of remyel<strong>in</strong>ation. The f<strong>in</strong>d<strong>in</strong>gs show that decl<strong>in</strong><strong>in</strong>g efficiencyof remyel<strong>in</strong>ation with age is largely due to failure of stem celldifferentiation. Evidence that the <strong>in</strong>nate immune response has a key role<strong>in</strong> remyel<strong>in</strong>ation led to an <strong>in</strong>terest<strong>in</strong>g discussion on the effects of anti<strong>in</strong>flammatorytherapy <strong>in</strong> multiple sclerosis.Sem<strong>in</strong>ars <strong>and</strong> WorkshopsA total of 10 symposia <strong>and</strong> 7 workshops provided platforms to discussaspects of research <strong>and</strong> diagnostic practice related to a wide range ofneurological/neurosurgical disorders. There were sessions dedicated toregenerative neuroscience <strong>and</strong> to bra<strong>in</strong> <strong>in</strong>flammation. A personal highlightwas the lecture by Professor Arie Perry <strong>in</strong> which he presented a verypractical approach to the subtyp<strong>in</strong>g of glioblastomas, with emphasis onthe cl<strong>in</strong>ical relevance of mak<strong>in</strong>g the dist<strong>in</strong>ctions.PostersOver two hundred posters, grouped <strong>in</strong>to ten themes, were displayed <strong>in</strong> theexhibition hall throughout the Congress, giv<strong>in</strong>g ample opportunity forA friendly encounter between congress participants<strong>in</strong> the exhibition hall.view<strong>in</strong>g. The st<strong>and</strong>ard was high <strong>and</strong> twenty-six poster presenters were<strong>in</strong>vited to give oral presentations with<strong>in</strong> the above symposia <strong>and</strong> workshops.In addition, there were two plenary poster discussions. For these,eight discussants were asked to reflect on what they had found of <strong>in</strong>terestamong the posters. I enjoyed the different approaches taken by the eight<strong>in</strong>dividuals to present their choices <strong>and</strong> see<strong>in</strong>g which strategies had mostsuccess <strong>in</strong> promot<strong>in</strong>g audience participation <strong>in</strong> the ensu<strong>in</strong>g discussions.Social EventsThe large exhibition hall provided a place to encounter old friends <strong>and</strong>make new acqua<strong>in</strong>tances. On day two the delegates were treated to anexclusive even<strong>in</strong>g reception <strong>in</strong> Ed<strong>in</strong>burgh Castle. This <strong>in</strong>cluded a chanceto view Scotl<strong>and</strong>’s Crown Jewels <strong>and</strong> experience the stirr<strong>in</strong>g sounds of apipe b<strong>and</strong> through the mist over Crown Square. The Gala D<strong>in</strong>ner was held<strong>in</strong> the newly refurbished National Museum of Scotl<strong>and</strong>, surrounded bythe eclectic W<strong>in</strong>dow on the World exhibition <strong>in</strong> the Gr<strong>and</strong> Gallery.Enterta<strong>in</strong>ment was provided by the excellent Kilter Ceilidh B<strong>and</strong> <strong>and</strong> Iobserved that many em<strong>in</strong>ent neuropathologists are also adept at Strip theWillow <strong>and</strong> other traditional dances performed that night.ConclusionsThe scientific programme was scheduled so that <strong>in</strong> general sessions witha bias towards cl<strong>in</strong>ical diagnostics ran alongside those with a more dedicatedresearch content. This allowed delegates to select the topics mostrelevant to their areas of <strong>in</strong>terest <strong>and</strong> there was truly ‘someth<strong>in</strong>g foreveryone’ throughout the Congress. Inevitably clashes occurred <strong>and</strong> sowe hopped between the auditoria to catch the anticipated highlights fromeach symposium <strong>and</strong> workshop. Some of the sessions suffered from lessthan strict timekeep<strong>in</strong>g, thus limit<strong>in</strong>g the opportunities for discussion <strong>and</strong>one of the plenary poster sessions had to be cut short. In the welcomeaddresses there had been references to the <strong>in</strong>clement weather <strong>and</strong> to therecent outbreak of Legionnaires’ disease <strong>in</strong> Ed<strong>in</strong>burgh. Nonetheless I amsure that most delegates rema<strong>in</strong>ed with<strong>in</strong> the Conference Centre eachday not because of these external factors but as a consequence of suchan <strong>in</strong>formative <strong>and</strong> enjoyable meet<strong>in</strong>g. lThe Abstracts of the 10th European Congress of Neuropathologyare published <strong>in</strong>: Cl<strong>in</strong>ical Neuropathology. 2012;31(4):232-5.Details of future Euro-CNS events, <strong>in</strong>clud<strong>in</strong>g the neuropathologytra<strong>in</strong><strong>in</strong>g courses, can be found at: www.euro-cns.orgACNR > VOLUME 12 NUMBER 4 > SEPTEMBER/OCTOBER 2012 > 33