Bioinformatics for DNA Sequence Analysis.pdf - Index of

Computational Gene Annotation 253Fig.12.3. Comparison between the protein and the gene predictionsThe product of the gene capicua in D. melanogaster has been previously mapped on the genome of D. yakuba. Thegraphical representation of the annotations has been obtained using the program GFF2PS (33).gene with 14 exons (Table 12.1). The length of the proteinproduct is 1,776 amino acids. Many predicted exons are supportedby a fragment of the protein from D. melanogaster (Fig. 12.3).We can compare the predictions obtained with these programs(exon coordinates) to study the common exons and the differencesin the results (Table 12.1). In addition, we can produce graphicalFig.12.4. Sequence alignment between the protein and the predicted geneThe prediction was obtained using the program GENEID (13). The alignment between the prediction and the protein(NP_524992) from D. melanogaster was performed with the program CLUSTALW (31). Only the first and the last exon areshown here, above and below the line, respectively.