2OO9 – 2O1O - Faculty of Dentistry - University of Otago
2OO9 – 2O1O - Faculty of Dentistry - University of Otago
2OO9 – 2O1O - Faculty of Dentistry - University of Otago
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The process <strong>of</strong> extracting RNA from paraffinembedded<br />
oral cancer tissues by one <strong>of</strong> our<br />
PhD candidates, Haizal Hussaini.<br />
Graph showing T cell anergy and tolerance genes that are up<br />
and down regulated in oral cancer, Source: Haizal Hussaini.<br />
Photomicrograph <strong>of</strong> inflamed connective tissue in a specimen <strong>of</strong><br />
periodontitis which has been frozen immediately after surgical removal and<br />
processed for double immun<strong>of</strong>luorescence. Numerous cells show surface<br />
positivity for CD8, a marker <strong>of</strong> T lymphocytes (red). A single cell, which is<br />
negative for CD8, is positive for interleukin (IL)-17 (green). This indicates<br />
that IL-17+ve cells are not CD8 + T cells. Original magnification x60. This<br />
work forms part <strong>of</strong> the PhD project <strong>of</strong> Praveen Parachuru. Praveen is<br />
investigating the role <strong>of</strong> regulatory T cells and Th17 cells in periodontal<br />
diseases in the Molecular Immunopathology Research Group.<br />
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