2OO9 – 2O1O - Faculty of Dentistry - University of Otago
2OO9 – 2O1O - Faculty of Dentistry - University of Otago
2OO9 – 2O1O - Faculty of Dentistry - University of Otago
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MARY CULLINAN<br />
BDS (Syd) MSc (Lond) FADI FICD<br />
Oral Sciences<br />
Research Associate Pr<strong>of</strong>essor<br />
In 2009/2010, Associate Pr<strong>of</strong>essor Cullinan has had<br />
published (or accepted for publication) a total <strong>of</strong><br />
21 research outputs, including 19 peer reviewed<br />
articles, one book chapter and one edited book. Her<br />
research platform has primarily been on the relative<br />
contribution <strong>of</strong> various microbiological, genetic and<br />
environmental (particularly smoking) risk factors to<br />
susceptibility to periodontal disease. More recently,<br />
this has involved utilising a metagenomic approach to<br />
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and disease, as well as gene expression studies looking<br />
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blood transcriptomes. Associate Pr<strong>of</strong>essor Cullinan has<br />
conducted several major longitudinal studies looking at<br />
clinical and molecular risk for periodontal disease and<br />
the impact <strong>of</strong> oral disease on systemic health, along with<br />
evaluation <strong>of</strong> a psychologically based health promotion<br />
programme. Her international reputation has led to<br />
invitations to co-edit a volume <strong>of</strong> the high-ranking dental<br />
journal Periodontology 2000 on the ‘Comparative biology<br />
<strong>of</strong> chronic and aggressive periodontitis’ and to contribute<br />
to reviews in Clinical Microbiology and Infection, the British<br />
Dental Journal and the Australian Dental Journal. As a result<br />
<strong>of</strong> her research, she was invited to be a keynote lecturer<br />
by the Philippines Society for Periodontology in 2009, The<br />
Royal Australasian College <strong>of</strong> Dental Surgeons and the<br />
Australian Society for Periodontology in 2010.<br />
Research and Collaboration<br />
Associate Pr<strong>of</strong>essor Cullinan’s research on understanding<br />
risk for oral disease involves utilizing a metagenomic<br />
approach and gene array technology to identify patient<br />
susceptibility to periodontal disease. Several major<br />
multidisciplinary longitudinal clinical studies are investigating<br />
the impact <strong>of</strong> various biological and psychosocial factors<br />
on oral health, the long-term effects <strong>of</strong> triclosan on thyroid<br />
function and on the progression <strong>of</strong> chronic periodontitis<br />
and the incidence <strong>of</strong> secondary cardiovascular events<br />
in patients with coronary heart disease. As part <strong>of</strong> her<br />
ongoing collaboration with Pr<strong>of</strong>essors NP Lang (<strong>University</strong><br />
<strong>of</strong> Hong Kong) and MJ Faddy (Queensland <strong>University</strong> <strong>of</strong><br />
Technology), Associate Pr<strong>of</strong>essor Cullinan is undertaking<br />
ante-dependence modelling <strong>of</strong> the famous Sri Lankan<br />
data set on the natural history <strong>of</strong> periodontal disease. In<br />
addition, she is involved in studies looking at the effect <strong>of</strong><br />
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the effect <strong>of</strong> delayed, early and immediate placement<br />
<strong>of</strong> implants in molar extraction sockets, the prevalence<br />
<strong>of</strong> periodontitis and oral characteristics in ankylosing<br />
spondylitis patients, and the impact <strong>of</strong> periodontal disease<br />
on oral-health-related quality <strong>of</strong> life among Omani teachers.<br />
Recent Publications<br />
Schätzle M, Faddy MJ, Cullinan MP, Seymour GJ, Lang NP,<br />
Bürgin W, Ånerud Å, Boysen H, Löe H. The clinical course<br />
<strong>of</strong> chronic periodontitis V. Predictive factors in periodontal<br />
disease. Journal <strong>of</strong> Clinical Periodontology 36: 365-371 (2009).<br />
Armitage GC, Cullinan MP. Comparison <strong>of</strong> the clinical<br />
features <strong>of</strong> chronic and aggressive periodontitis.<br />
Periodontology 2000 53: 12-27 (2010).<br />
Bohnstedt S, Cullinan MP, Ford PJ, Palmer JE, Leishman SJ,<br />
Westerman B, Marshall RI, West MJ, Seymour GJ. High<br />
Antibody Levels to P.gingivalis in Cardiovascular Disease.<br />
Journal <strong>of</strong> Dental Research 89: 938-942 (2010).<br />
Oral Biology. Molecular techniques and applications. Eds<br />
GJ Seymour, MP Cullinan, NCK Heng. Springer New York<br />
(2010).<br />
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