MALDI Q-Tof Premier Operators Guide - Waters

Cleaning and replacing the vacuum lock O-ringWarning: The instrument components are liable to becontaminated with biologically hazardous and toxic materials.Wear rubber gloves at all times while handling the components.If the sample plate carrier fails to pump the plate carrier lid within the 3minute system time-out period, a plate carrier error will occur.The time out can be caused by either• The lid failing to seat correctly on the vacuum lock o-ring• The vacuum lock o-ring has failed or is contaminated.To remove and clean the O-ring:1. Unload the sample plate and open the plate carrier lid.2. Lift the O-ring off the spigot.3. Clean the O-ring and its seating surface with a lint-free cloth andsuitable solvent, such as methanol.4. Clean the inside surface of the lid as described in step 3. Ensure that nohairs or particles remain.Examine the integrity of the O-ring. If it is in good condition, refit it,seating it evenly around the spigot. If its condition is in any doubt, fit anew O-ring.Cleaning and replacing the vacuum lock O-ring 4-3