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X HIV/AIDS Prevention and Care in Resource-Constrained Settings

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F igure 13<strong>HIV</strong> Seroprevalence <strong>in</strong> AdultPopulations at the End of 2000■Rank Country %PrevalenceAFRICA1 Botswana 362 Swazil<strong>and</strong> 253 Zimbabwe 254 Lesotho 245 Zambia 206 South Africa 207 Namibia 208 Malawi 169 Kenya 1410 Central African 14Republic11 Mozambique 1312 Djibouti 1213 Burundi 1114 Rw<strong>and</strong>a 1115 Cote d’Ivoire 1116 Ethiopia 1117 Ug<strong>and</strong>a 818 United Rep. of 8Tanzania19 Cameroon 820 Burk<strong>in</strong>a Faso 621 Congo 622 Togo 623 Dem. Republic 5of Congo24 Nigeria 525 Gabon 426 Ghana 427 Sierra Leone 328 Eritrea 329 Liberia 330 Angola 331 Chad 332 Gu<strong>in</strong>ea-Bissau 3Gender vulnerability: For both biological <strong>and</strong>socioeconomic reasons, girls <strong>and</strong> women are particularlyvulnerable to <strong>HIV</strong>/<strong>AIDS</strong>. To counter these<strong>in</strong>herent gender <strong>in</strong>equities, <strong>in</strong>novative programshave been implemented that <strong>in</strong>volve a range ofactivities—such as improv<strong>in</strong>g girls’ access to basiceducation, provid<strong>in</strong>g women with microf<strong>in</strong>anceopportunities <strong>and</strong> modify<strong>in</strong>g or adapt<strong>in</strong>g culturalRank Country %PrevalenceAFRICA — cont<strong>in</strong>ued33 Ben<strong>in</strong> 234 Mali 235 Gambia 236 Senegal 237 Gu<strong>in</strong>ea 238 Niger 1LATIN AMERICA / CARIBBEAN1 Haiti 52 Bahamas 43 Guyana 34 Dom<strong>in</strong>ican 3Republic5 Belize 26 Honduras 27 Panama 28 Guatemala 19 Sur<strong>in</strong>ame 110 Barbados 111 Tr<strong>in</strong>idad <strong>and</strong> 1TobagoASIA AND THE NEAR EAST1 Cambodia 42 Thail<strong>and</strong> 23 Myanmar 24 Sudan 1EUROPE AND EURASIAUkra<strong>in</strong>e 1■■practices <strong>and</strong> legislation that canempower women. But the realimpact of these programs hasyet to be determ<strong>in</strong>ed.The scale of <strong>in</strong>terventions:Exist<strong>in</strong>g prevention programsare not large enough. It is likelythat prevention services reachonly 10 percent of the world’svulnerable populations. Thislack of scale is further complicatedby the fact that the globalcommunity urgently needs abetter underst<strong>and</strong><strong>in</strong>g of thenumbers of persons (coveragewith<strong>in</strong> a targeted community)<strong>and</strong> level of behavior change(e.g., condom use <strong>in</strong> casual relations)that must be reached toachieve measurable changes <strong>in</strong><strong>in</strong>cident <strong>in</strong>fections.Basic care <strong>and</strong> support:Incorporat<strong>in</strong>g basic care <strong>and</strong>support for <strong>HIV</strong>-<strong>in</strong>fected <strong>in</strong>dividuals,their families <strong>and</strong> theirsurvivors (orphans), as well as<strong>in</strong>troduc<strong>in</strong>g new <strong>in</strong>terventions—suchas the short-courseARV regimens to reduceMTCT—must be done <strong>in</strong> waysthat will enhance rather th<strong>and</strong>im<strong>in</strong>ish the primary preventionagenda.■ The need for vacc<strong>in</strong>es <strong>and</strong>microbicides: There is still alack of critical technologies thatwould radically alter our abilityto reduce new <strong>in</strong>fections <strong>and</strong>provide compassionate care tothe <strong>in</strong>fected. These <strong>in</strong>cluderapid, simple diagnostics for STDs; a vag<strong>in</strong>almicrobicide; simpler, cost-realistic ARV regimens;<strong>and</strong>, most important of all, an effective preventivevacc<strong>in</strong>e. We urgently need an <strong>HIV</strong> vacc<strong>in</strong>e <strong>and</strong> aneffective topical microbicide. Our exist<strong>in</strong>g <strong>in</strong>terventionsdo work, if implemented properly <strong>and</strong> toscale. But these additional tools would make anenormous difference <strong>in</strong> our ability to combat<strong>HIV</strong>/<strong>AIDS</strong>.XXIV <strong>HIV</strong>/<strong>AIDS</strong> <strong>Prevention</strong> <strong>and</strong> <strong>Care</strong> <strong>in</strong> <strong>Resource</strong>-Constra<strong>in</strong>ed Sett<strong>in</strong>gs

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