NMS Q&A Family Medicine

chapter 56Drug Interactions, Caveats,and Primary CareExamination questions: Unless instructed otherwise, choosethe ONE lettered answer or completion that is BEST ineach case.1 A 25-year-old male complains of a mildly pruriticrash that appears on the trunk as evenly distributedovoid papulosquamous lesions. Besides pityriasisrosea, each of the following drugs may precipitatethis rash as an expression of allergy except for whichone?(A) Captopril(B) Barbiturates(C) Sulfonamides(D) Metronidazole(E) Metoprolol2 A middle-aged male has been diagnosed with onychomycosisand wishes to be rid of the troublesomebilateral great toe subungual accumulations ofsloughed squamous material. The patient takes severalmedications. Each of the following drugs or categoriesof drugs should be considered for loweringtheir current dosages except which one?(A) Tricyclic antidepressants(B) Beta-adrenergic blocking agents(C) Selective serotonin reuptake inhibitors (SSRIs)(D) Ethinyl estradiol(E) Class C antidysrhythmia drugs3 A 55-year-old male patient with treated hypertensionhas been referred to a psychiatrist for bipolar disorder.He returns within a few weeks for his routine follow-upvisit, having been placed on lithium carbonate. Eachof the following drugs is relatively contraindicated inthis patient due to the danger of precipitating toxicityof lithium except for which one?(A) Acetazolamide(B) Hydrochlorothiazide(C) Carbamazepine(D) Lisinopril(E) Metronidazole4 Symmetrel (amantadine) is indicated in two quitedifferent types of conditions: prophylaxis against andtreatment of influenza A and extrapyamidal centralnervous system (CNS) disease and extrapyramidaldrug side effects. Which of the following drugs orpreparations given simultaneously with amantadinehas been shown to worsen the tremor of Parkinsondisease?(A) Hydrochlorothiazide/triampterene(B) Amitriptyline(C) Benztropine(D) Thioridazine(E) Trihexyphenidyl5 A 34-year-old woman has been diagnosed with type2 diabetes, with a 2-hour postprandial blood sugarlevel of 160 mg/dL. Her glycohemoglobin is 8% ofthe total. She has had no operations, and her health isunremarkable except for her moderate obesity. Thefamily doctor plans to start metformin. Which of thefollowing must be measured before commencingwith this plan?(A) Complete blood cell count(B) Liver function battery(C) Lipid screen(D) Serum creatinine(E) Chest x-ray6 Regarding the patient in Question 5, she has beenstarted on metformin 500 mg twice daily. The familydoctor considers placing her on an angiotensinconvertingenzyme inhibitor (ACEI) to maximizepreservation of renal function in a diabetic. Thepatient says that she is attempting to achieve pregnancy.Which of the following is a strict contraindicationto this drug?(A) Chronic renal failure(B) Chronic obstructive lung disease(C) Pregnancy in the second trimester(D) Asthma(E) Pregnancy in the first trimester325