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Double Robustness in Estimation of Causal Treatment Effects

Double Robustness in Estimation of Causal Treatment Effects

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Complication: Confound<strong>in</strong>g<br />

1. Introduction<br />

• The fact that a subject was exposed or not is associated with<br />

subject characteristics that may also be associated with his/her<br />

potential outcomes under treatment and control<br />

• To estimate the average causal effect from observational data<br />

requires tak<strong>in</strong>g appropriate account <strong>of</strong> this confound<strong>in</strong>g<br />

Challenge: Estimate the average causal treatment effect from<br />

observational data , adjust<strong>in</strong>g appropriately for confound<strong>in</strong>g<br />

• Different methods <strong>of</strong> adjustment are available<br />

• Any method requires assumptions ; what if some <strong>of</strong> them are wrong ?<br />

• The property <strong>of</strong> double robustness <strong>of</strong>fers protection aga<strong>in</strong>st some<br />

particular <strong>in</strong>correct assumptions. . .<br />

• . . . and can lead to more precise <strong>in</strong>ferences<br />

<strong>Double</strong> <strong>Robustness</strong>, EPID 369, Spr<strong>in</strong>g 2007 4

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