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Acknowledgments<br />

I thank my supervisor Pr<strong>of</strong>. Dr. Gerd Bicker for allow<strong>in</strong>g me to work <strong>in</strong> an excit<strong>in</strong>g project and for<br />

his excellent guidance throughout my PhD project. Dur<strong>in</strong>g my stay <strong>in</strong> your laboratory I have<br />

learned not only how to become a good researcher but also a mentor. Thank you very much!<br />

I also extend my s<strong>in</strong>cere gratitude to my advisory group Pr<strong>of</strong>. Dr. Stephan Ste<strong>in</strong>lechner and Pr<strong>of</strong>.<br />

Dr. Herbert Hildebrandt for the useful discussion, suggestion and guidance throughout my doctoral<br />

process.<br />

I thank Pr<strong>of</strong>. Dr.med. Ellen Fritsche and Dr. Thomas D<strong>in</strong>o Rockel (Group <strong>of</strong> Molecular Toxicology,<br />

Institut für Umweltmediz<strong>in</strong>ische Forschung, He<strong>in</strong>rich He<strong>in</strong>e-University, Dusseldorf, Germany) for<br />

permitt<strong>in</strong>g me to work on fetal human neural progenitor cells and cont<strong>in</strong>uous collaboration<br />

throughout this project.<br />

I thank ZSN PhD commission specially Pr<strong>of</strong>. Dr. Wolfgang Löscher, Pr<strong>of</strong>. Dr. Wolfgang<br />

Baumgartner and the coord<strong>in</strong>ation <strong>of</strong>fice (Dr. Dagmar Esser, Nadja Borsum and Manuela<br />

Chambers) for cont<strong>in</strong>uous support throught my doctoral study. I also s<strong>in</strong>cerely thank the M<strong>in</strong>istry<br />

for Science and Culture <strong>of</strong> Lower Saxony for giv<strong>in</strong>g me the Georg-Christoph-Lichtenberg<br />

scholarship throughout my PhD study.<br />

My stay <strong>in</strong> cell biology group could not be as fruitful as it is without the support and pleasant<br />

environment created by present and past colleagues <strong>in</strong> the lab. I thank Dr. Micheal Stern for his<br />

constructive comments, suggestion and discussion. I thank Saime Tan for her excellent technical<br />

support. I am also thankful to Dr. Sab<strong>in</strong>e Knipp and Dr. Grzegorz Podrygajlo for useful discussion.<br />

My thanks also go to Arne Pätschke, Andrea Gierse, Rene Eickh<strong>of</strong>f, Nicole Böger, Frank Rol<strong>of</strong>f<br />

and Christ<strong>in</strong>a Lorbeer.<br />

Last but not least I thank my family; Lydia and Betania. Thank you very much Lydia for the love,<br />

courage and support you gave me throughout this work. Betu you helped a lot by stay<strong>in</strong>g long <strong>in</strong> the<br />

k<strong>in</strong>dergarten. Thank you for your patience.<br />

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