POLARIS GC/MS

Direct Probe ANALYSIS key applications: • Research
• Chemical synthesis
• Natural products
Direct Insertion – Antibiotics
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
98.2
116.1
123.2
132.1
158.2
174.1
(M) Erythromycin - MW 733
176.1
365.1
383.1
179.1 557.3 648.3
715.3
221.1 307.2 334.2
490.2
522.2 660.3
239.1 289.2 384.1
411.0 464.3 574.3
495.2 602.3
644.4 661.4 716.4
100 150 200 250 300 350 400 450 500 550 600 650 700 750
m/z
Direct probe analysis combined with MS/MS can quickly determine the presence of a drug, carcinogen,
endocrine disrupter, or priority pollutant in any matrix without the need for sample preparation or
chromatography.
HO
HO
O
472.2
OH
O O
O
N
OH
558.3
Interchangeable probes for non-GC applications
O
O
O
OH
O
Direct Exposure – DEP
Direct Insertion – DIP
Direct probe mass spectrometry is an
alternative sampling technique when
the sample material cannot pass
through a capillary GC column.
Some examples include sugars, long
chain amino acids, small proteins and
triglycerides. The spectrum of these
compounds can be obtained by placing
the sample onto a probe tip and
inserting the probe directly into the
mass spectrometer.
The direct sample probe can also be
used as a screening tool when
combined with MS/MS. A complex
sample such as soil, blood, hair or
other biological material can be placed
directly onto the probe. By using
MS/MS, the presence or absence of
particular target analytes can be
determined. This efficient technique
eliminates tedious sample preparation
and gas chromatographic analysis,
saving cycle time and money.
Finnigan Polaris offers the
chromatographer a wealth
of fast, powerful and reliable
solutions. Come join us in
the company of scientists –
you’ll see the difference
in your data.