New insights into the management of severe sepsis and septic shock
New insights into the management of severe sepsis and septic shock
New insights into the management of severe sepsis and septic shock
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Early haemodynamic optimization(resuscitation bundle) In 2001, a trial <strong>of</strong> early hemodynamicresuscitation to normal physiologicparameters, or early goal-directed <strong>the</strong>rapy,was conducted in ED patients with <strong>severe</strong><strong>sepsis</strong>/<strong>septic</strong> <strong>shock</strong> <strong>and</strong> revealed asignificant mortality reduction. Early goal-directed <strong>the</strong>rapy is an algorithmicapproach to hemodynamic optimization <strong>and</strong>resolution <strong>of</strong> global tissue hypoxia within<strong>the</strong> first 6 hours <strong>of</strong> disease presentation
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