New insights into the management of severe sepsis and septic shock
New insights into the management of severe sepsis and septic shock
New insights into the management of severe sepsis and septic shock
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Antimicrobial <strong>the</strong>rapy Administration <strong>of</strong> antibiotics within <strong>the</strong> time<strong>of</strong> ED care <strong>and</strong> as soon as possible once<strong>the</strong>re is a reasonable suspicion <strong>of</strong> <strong>severe</strong><strong>sepsis</strong> is likely to increase <strong>the</strong> chance <strong>of</strong>favourable outcome compared with lateradministration (Grade E) Empirical regimens should be sufficientlybroad, so <strong>the</strong>re is little chance (less than5%) that <strong>the</strong> <strong>of</strong>fending pathogen will not beeffectively covered
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