New insights into the management of severe sepsis and septic shock

Surviving Sepsis: New Recommendationsfor Vasopressors Authors strongly recommend norepinephrineas the first choice for vasopressor therapy(Grade 1B). Vasopressin 0.03 units / minute isan alternative to norepinephrine, or may beadded to it (Grade 2A). When a second agent is needed, epinephrine istheir weakly-recommended vasopressor choice(Grade 2B). Dopamine was only recommended in highlyselected patients whose risk for arrhythmiaswas felt to be very low and who had a lowheart rate and/or cardiac output (Grade 2C).