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<strong>Pharmacokinetics</strong>Analysis of experimental data...1987654321987654321This sheet of semi-log graph paper can be used to answer Question (1).6.4 Appendix 1We know that falling drug concentration can be described by the equation:C t= C 0x e -KtIf we take the natural logs of both sides of the equation we get …Download free ebooks at bookboon.com64
<strong>Pharmacokinetics</strong>Analysis of experimental data...Ln(C t) = Ln(C 0) – K.tThis can then be re-arranged to:Ln(C t) = -K . t + Ln(C 0)This is now in the same form as the general equation of a straight lineY = m . X + cGeneral equation Y = m . X + cThis case Ln(C t) = -K . t + Ln(C 0)ThusY (the value plotted up the vertical axis) will be Ln(C t)m (the gradient of the line) will be –KX (the value plotted along the horizontal axis) will be tc (the intercept on the vertical axis) will be Ln(C 0)I joined MITAS becauseI wanted real responsibiliThe Graduate Programmefor Engineers and GeoscientistsMaersk.com/MitasPlease click the advertReal workInternational al opportunitiesThree work placementsMonth 16I was aconstructionsupervisor inthe North Seaadvising andhelping foremensolve problems65Download free ebooks at bookboon.com
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