Pros and Cons of Bayesian Pharmacometric Modeling Using BUGS

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Computational tools/methods for Bayesian modelingBUGS language MCMC programsBUGS language MCMC programsWinBUGS 1.4.3OpenBUGS 3.0.5Probable successor to WinBUGS 1.4.*Source code availablePrimarily a Windows application, but a non-GUI version is availablefor Linux systems with Intel/AMD processorsActive development. Currently a beta version.Release of a stable version imminent.More functions and distributions.Improved existing samplers and added moreDifferent approach to selecting samplersJAGSc○2009 Metrum Institute Bayesian Modeling Using BUGS AAPS 2009 9 / 26
Computational tools/methods for Bayesian modelingBUGS language MCMC programsBUGS language MCMC programsWinBUGS 1.4.3OpenBUGS 3.0.5JAGSJAGS = Just Another Gibbs SamplerWritten in C++, so is more platform-independentUsually run from R via the rjags packagec○2009 Metrum Institute Bayesian Modeling Using BUGS AAPS 2009 9 / 26
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Pros and Cons of Bayesian Pharmacometric Modeling Using BUGS

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