13.07.2015 Views

Pros and Cons of Bayesian Pharmacometric Modeling Using BUGS

Pros and Cons of Bayesian Pharmacometric Modeling Using BUGS

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<strong>BUGS</strong>ModelLibraryBuilt-in models<strong>BUGS</strong> model using a built-in <strong>BUGS</strong>ModelLibrary functionmodel{for ( i in 1:nSubjects){# Inter-patient variation in PK parameters# theta[1:5] = (CL, Q, V1, V2, ka - lambda1)logtheta[ i , 1:5] ∼ dmnorm(logthetaMean[i, 1:5], omega.inv[1:5, 1:5])for ( j in 1:5){log(theta[ i , j ])

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