Do We Need A Roadmap or GPS?, Dr. Robert Gish - Hepatitis B ...
Do We Need A Roadmap or GPS?, Dr. Robert Gish - Hepatitis B ...
Do We Need A Roadmap or GPS?, Dr. Robert Gish - Hepatitis B ...
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Real W<strong>or</strong>ld: Insurance and costrestraints, part 1• Use the most powerful <strong>or</strong>al single medication with thelowest rate of resistance– Monotherapy with ETV appropriate f<strong>or</strong> >90% oftreatment naïve• Expect comparable TDF data: approval in US pending– Lamivudine as primary Rx?• up to 80% of patients will need combination therapy• ADF + LAM = ETV costs in most countries– Adefovir: 40-60% will need add-on therapy due to risk(<strong>or</strong> presence) of resistance <strong>or</strong> lack of 1 year primaryresponse
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