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Immunology as a Metaphor for Computational ... - Napier University

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Chapter 3. Immune Systems <strong>for</strong> Scheduling 92707060Antigen Exposure Rate = 260Antigen Exposure Rate = 8Number of antibodies5040302010Number of antibodies504030201001 2 3 4 5 6 7 8 9 10Number of antigens matched01 2 3 4 5 6 7 8 9 10Number of antigens matchedFigure 3.18: Match Threshold 2 : Number of antibodies matching B1 antigen <strong>for</strong>antibody sample size = 30. The graphs compare the overlap when τ C 2 and τ C 83.13.3 Me<strong>as</strong>uring OverlapThe two previous sections have shown that it is possible to evolve a set of unique antibodies,and also that those antibodies tend to match at le<strong>as</strong>t one antigen. In order tome<strong>as</strong>ure how much overlap is occurring between those antibodies however, the numberof antigens matched by each antibody in the population is recorded. Figure 3.18shows the number of antibodies that match n antigens, where n takes values between1 and 10. The diagram contr<strong>as</strong>ts the results obtained <strong>for</strong> a match-threshold of 2 andfixed antibody sample size C σ 30 <strong>for</strong> various values of τ. Clearly, more antigens arematched at high values of τ, <strong>as</strong> expected.It is interesting to observe how the number of antibodies matching more than 1antigen incre<strong>as</strong>es <strong>as</strong> the GA runs. The graphs in figure 3.19 illustrate the point. Experimentsare per<strong>for</strong>med in which the match-threshold m is varied from 2 to 5, <strong>for</strong>populations of antibodies in which the antibody length is varied from m to 5 also.When the match-threshold is equal to the antibody length, there is a rapid incre<strong>as</strong>e inthe number of matching antibodies in the C m 2 c<strong>as</strong>e after which the number remainsrelatively constant. For C m 3, the number rises steadily. For values of D m l, in eachc<strong>as</strong>e, there is an immediate incre<strong>as</strong>e at the the start of each run to a level which is maintainedthroughout the remainder of the experiment. The initial rise is more pronouncedwhen m is significantly less than l.

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