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Immunology as a Metaphor for Computational ... - Napier University

Immunology as a Metaphor for Computational ... - Napier University

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Chapter 2BackgroundThis chapter begins with a brief introduction to immunology, necessary to set the scene<strong>for</strong> the remainder of the thesis. It is of course a v<strong>as</strong>t topic, and only the most relevantfeatures are covered here. For a more detailed overview, the interested reader isreferred to an introductory immunology text such <strong>as</strong> [Roitt et al., 1988]. This introductionis followed by a review and comparison of existing AIS implementations, andan overview of existing literature in the application of immune systems to the chosendomains of scheduling and data-clustering. Finally, there is a discussion of the relationshipof the immune system to a cl<strong>as</strong>s of <strong>as</strong>sociative memories known <strong>as</strong> SparseDistributed Memories.2.1 B<strong>as</strong>ic <strong>Immunology</strong>This section presents some b<strong>as</strong>ic immunological concepts which are central to theadaptive immune response. As already stated, it is with this <strong>as</strong>pect of the immune systemthat most artificial systems are concerned. Key to all adaptive responses is a cl<strong>as</strong>sof cells known <strong>as</strong> lymphocytes which specifically recognise individual pathogens, regardlessof the location of those pathogens, whether in blood, tissue fluids or actuallyinside host cells. Lymphocytes fall into two categories, T-Cells (Thymus dependent),and B-Cells, (Bone marrow dependent). The function of the B-Cell is to attack extracellularpathogens by rele<strong>as</strong>ing antibodies, i.e. specific molecules which recognise and10

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