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Diekema.ppt [Compatibility Mode] - Institute of Medicine

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Updated VSD Analysis, August, 2011<br />

• New method for estimating attributable risk<br />

• Uses information on baseline risk for seizures by<br />

age in months from the entire VSD population<br />

(provides more stable estimates), rather than<br />

estimating baseline risk from the control period<br />

for broad age intervals (where there are fewer<br />

cases and more uncertainty about baseline risk<br />

estimates despite the broad age interval).<br />

• Highlights substantial variation in AR by age in<br />

months, which is due to the variability in baseline<br />

risk by age in months.

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