Diekema.ppt [Compatibility Mode] - Institute of Medicine

October 2011 ACIP Meeting
General Recommendations Working Group
Febrile Seizures Subgroup - Assessment
• Unclear if risk after simultaneous administration of TIV
and PCV13 is greater than with separate administration
• Unclear if association between influenza vaccine and
febrile seizures is unique to 2010-2011 vaccine strains
• Cases with concurrent infection not excluded from
analysis
• Relatively small numbers of cases
• Further investigation is underway to determine if other
vaccines besides TIV and PCV13 may be contributing to
the febrile seizures
• Evaluation of confounding or effect modification by concomitant
administration of DTaP with PCV13 or TIV
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