Diekema.ppt [Compatibility Mode] - Institute of Medicine

Risk difference per 100,000 doses
Attributable Risk (AR) estimates for febrile seizures
following 1 st dose TIV, 2010-11 ^ (Updated AUG 2011)
60
50
40
30
20
10
0
6 78910
TIV without concomitant PCV13* PCV13 without concomitant TIV*
Concomitant TIV + PCV13*
45/100,000 (~1 excess febrile seizure in 2222 vaccinees)
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
11
12
13
14
15
Age in months
^Tse A and Lee G for the VSD
*Vaccines may have been received concomitantly with non-TIV, non-PCV13 vaccines