Diekema.ppt [Compatibility Mode] - Institute of Medicine
Diekema.ppt [Compatibility Mode] - Institute of Medicine
Diekema.ppt [Compatibility Mode] - Institute of Medicine
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13-valent Pneumococcal Conjugate Vaccine<br />
(PCV13)<br />
• Introduced into routine schedule in March 2010<br />
• Replaced PCV7, which was associated with<br />
prevention <strong>of</strong> 211,000 cases <strong>of</strong> IPD during 2000-<br />
2007 (Pilishvili JID 2010)<br />
• Recommended for all children at 2, 4, 6, and 12-15<br />
months<br />
• Relevance <strong>of</strong> booster dose in 2 nd year <strong>of</strong> life:<br />
•Additional individual protection over primary series<br />
•Likely important for mucosal immunity (pneumonia, otitis)<br />
•Considered important for reducing transmission to other<br />
age groups