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Catalytic Reductive Coupling Reactions - Michigan State University

Catalytic Reductive Coupling Reactions - Michigan State University

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Nickel Catalyzed <strong>Coupling</strong> <strong>Reactions</strong>PhOR 1Ni(COD) 25 mol%PhOLNiLR 1Bu 2 Zn/BuZnClOPhaBuR 1PPh 325 mol %OPhHR 1bentry ligand R1 yield (%a) yield (%b)1 - H 51 112 - Ph 68 83 PPh3 H 0 924 PPh3 Ph 19 475 PPh3 Bu 16 58Montgomery, J.; Savchenko, A. J. Am. Chem. Soc. 1996, 118, 2099—2100.

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