Catalytic Reductive Coupling Reactions - Michigan State University

Mechanism via Oxidative CyclometallationX = OAc, OBzRMHXRMXHM = [Rh III ] +OOOOX = Cl, BrRMXHOOYPdX 32-X -YPdX 43-trans-elimination-X - Rates of heteroatom (Y) elimination:Y -PdX 42-β−halide > β−OAc > β−OR > β−OH ~ β−HTong, X.; Li, D.; Zhang, Z.; Zhang, X. J. Am. Chem. Soc. 2004, 126, 7601—7607.Zhang, Z.; Lu, X.; Xu, Z.; Zhang, Q.; Han, X. Organometallics 2001, 20, 3724—3728.