Hyaluronic Acid

DSC Thermal AnalysisThe main DSC characteristics, i.e. Tcc((-) 1.01°C), Tm ((-) 0.80°C and Tg((+)30.29°C) were shifted to lowertemperatures compared to hexyloxymodified HA. A new endothermic peaktemperature at (+) 5.57°C ischaracteristic for the transition fromthe liquid crystalline state to theisotropic liquid state (T*).The appearance of the T* peaktemperature in 6.97 mol.%modified pentadecyloxyhyaluronatecan be explained bythe occurance of the liquid crystalphase transition induced by themicelles ordering processproceeding in the system due tothe electrostatically inducedtemporary lattice formation.Heat Flow (W/g)-1.48-1.50-1.52-1.54ExoT mT CCT *Liquid Crystal Phase-1.56-20 -10 0 10 20 30 40Temperature (°C)DSC heating curve of the 6.97 mol.% modifiedpentadecyloxy-HA.T g42