Post-transcriptional control of gene expression
Post-transcriptional control of gene expression
Post-transcriptional control of gene expression
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A model for nonsense-mediated mRNA decayNuclear proteins mark the exon-exonboundaries on a spliced mRNA molecule.These proteins are thought to assemble inconcert with the splicing reaction and mayalso be involved in the transport <strong>of</strong> maturemRNAs from the nucleus50-54 nt"test" round <strong>of</strong> translation isperformed by the ribosomesurveillance proteinsIf an in-frame stop codon is encountered before the final exon-exon boundary isreached, the mRNA is subject to nonsense-mediated decay.
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