Post-transcriptional control of gene expression
Post-transcriptional control of gene expression
Post-transcriptional control of gene expression
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
siRNA and miRNA• Two classes <strong>of</strong> short dsRNA molecules:– small interfering RNA (siRNA), Exogenous origin (ex. viral)– microRNA (miRNA), Endogenous originhave been identified as sequence-specificpost<strong>transcriptional</strong> regulators <strong>of</strong> <strong>gene</strong> <strong>expression</strong>.• siRNA and miRNA are incorporated into relatedRNA-induced silencing complexes (RISCs)(siRISC and miRISC)RLC(Risc loading complex)
Change language