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AdministrationUCCRC Executive CommitteeMichelle M. Le Beau, PhDDirectorProfessor of MedicineDirector, Cancer Cytogenetics LaboratoryMarcy A. L ist, PhDAssociate Director for AdministrationScientific Director, Cancer ClinicalTrials OfficeMarsha R. Rosner, PhDDeputy Director for Basic SciencesCharles B. Huggins ProfessorDirector, Ben May Department forCancer ResearchProfessor of Neurobiology, Pharmacologyand PhysiologyEverett E. Vokes, MDDeputy Director for Clinical SciencesJohn E. Ultmann ProfessorChairman of MedicineHabibul Ahsan, MDAssociate Director for Population ResearchProfessor of Health StudiesGeoffrey L. Greene, PhDAssociate Director for Basic Sciencesand EducationVirginia and D.K. Ludwig ProfessorAssociate Director, Ben May Departmentfor Cancer ResearchRick A. Kittles, PhDAssociate Director for Diversity andCommunity OutreachAssociate Professor of MedicineYves Lussier, MDDirector for Biomedical InformaticsAssociate Professor of MedicineMedicine Director, Center forBiomedical InformaticsMark J. Ratain, MDAssociate Director for Clinical SciencesLeon O. Jaobson Professor of MedicineChair, Committee on ClinicalPharmacology and PharmacogenomicsAdditional UCCRC SeniorLeaders and Members of theCancer Advisory CommitteeJulie A. Auger, BSAssociate Director for Core FacilitiesExecutive Director, Office of SharedResearch FacilitiesJohn Cunningham, MDProfessor and Section Chief of PediatricHematology/OncologyCarol S. Giometti, PhDBiosciences DirectorArgonne National LaboratoryOlufunmilayo Olopade, MBBSWalter L. Palmer Distinguished ServiceProfessor of MedicineAssociate Dean for Global MedicineMitchell C. Posner, MDThomas D. Jones Professor and Chiefof General SurgeryRichard L. Schilsky, MDProfessor of MedicineArieh Shalhav, MDFritz and Mary Lee Duda Chair,Professor and Chief of UrologyGary Steinberg, MDProfessor of SurgeryMichael Vannier, MDProfessor of RadiologyRalph Weichselbaum, MDDaniel K. Ludwig Professor andChairman of Radiation andCellular OncologyS. Diane Yamada, MDAssociate Professor of Obstetricsand GynecologyChief, Section of Synecological OncologyUCCRC Senior StaffPaul Butera, PhDDirector for CommunicationsMary Ellen Connellan, MSExecutive Director,Cancer Research FoundationHoyee Leong, PhDDirector for Scientific Communicationsand Strategic PartnershipsMaria Reyes, BSDirector for FinanceConnie Skosey, RNDirector for Clinical OperationsUmberto Tachinardi, MDDirector for Informatics
Overview &AdministrationUCCRC –External Advisory BoardJames K. Willson, MD (CHAIR)Director, Harold Simmons Cancer CenterUniversity of Texas SouthwesternMedical Center at DallasDonald Berry, PhDProfessor & Chair, Departmentof BiostatisticsM.D. Anderson Cancer CenterMichael A. Caligiuri, MDDirector, The Ohio State UniversityComprehensive Cancer CenterMary B. Daly, MD, PhDSenior VP for Population ScienceDirector, Cancer Prevention andControl ProgramFox Chase Cancer CenterStephen H. Friend, MD, PhDSenior Vice PresidentMerck & Co., Inc.Stanton L. Gerson, MDDirectorCase Comprehensive Cancer CenterSteven D. Gore, MDProfessor of OncologySidney Kimmel Comprehensive CancerCenter at Johns HopkinsPhilip D. Greenberg, MDProfessor of Medicine and ImmunologyUniversity of WashingtonH. Kim Lyerly, MDDirectorDuke Comprehensive Cancer CenterGloria Petersen, PhDProfessor of EpidemiologyMayo Clinic College of MedicineStephen E. Sallan, MDChief of Staff – Chief Medical Officer,Childrens Hospital Cancer CareDana-Farber Cancer InstituteMargaret R. Spitz, MDProfessor and ChairDepartment of EpidemiologyM D Anderson Cancer CenterDaniel Sullivan, MDProfessor, Department of RadiologyDuke University Medical SchoolMichael J. Weber, PhDDirector, Cancer Center at theUniversity of Virginia Health SystemJane Wegenke, BSAssociate Director – AdministrationUniversity of Wisconsin ComprehensiveCancer CenterMichael J. Welch, PhDProfessor of RadiologyDepartment of RadiologyWashington University Schoolof MedicineScott J. Leischow, PhDProfessor, Colleges of Medicine andPublic HealthArizona Cancer Center -The Universityof ArizonaC. Clifton Ling, PhD(Ad Hoc Imaging)Head, Radiation Biophysics LaboratoryMemorial Sloan-Kettering Cancer CenterUCCRC SCIENTIFIC REPORT 20095
Page 1 and 2: Collaborate Explore Discover2008-20
Page 3 and 4: Immunology& CancerClinical & Experi
Page 8 and 9: Program 1Cell Signaling and Gene Re
Page 10 and 11: 8MembersInvestigator*Kenneth Alexan
Page 12 and 13: Theme: Molecular Mechanisms of Apop
Page 14 and 15: Theme: Cell Motility, Cell-Cell Adh
Page 16 and 17: Theme: Systems Biology and Genetic
Page 18 and 19: Theme: Developmental BiologyIlaria
Page 20 and 21: Additional Program Highlights*Resea
Page 22 and 23: Selected Publications* : Intraprogr
Page 24 and 25: Lang D, Mascarenhas JB, Powell SK,
Page 26 and 27: Granovsky AE, Rosner MR. Raf kinase
Page 28 and 29: Selected Major Grants and AwardsThe
Page 30 and 31: Program 2Molecular Genetics and Hem
Page 32 and 33: MembersInvestigator*John Anastasi M
Page 34 and 35: Theme: Pathogenesis of LeukemiaDoro
Page 36 and 37: The ultimate goals of the laborator
Page 38 and 39: Additional Program Highlights*Resea
Page 40 and 41: Selected Publications* : Intraprogr
Page 42 and 43: * Knight JA, Skol AD, Shinde A, Has
Page 44 and 45: * # Gordon MK, Sher D, Karrison T,
Page 46 and 47: Program 3Immunology and CancerScann
Page 48 and 49: MembersInvestigator*Erin Adams PhDM
Page 50 and 51: and αβ TCRs are well known, the l
Page 52 and 53: transcriptional profile in the tumo
Page 54 and 55: ••The impact of regulatory T ce
Page 56 and 57:
Selected Publications* : Intraprogr
Page 58 and 59:
Storb, Ursula MD# Longerich S, Orel
Page 60 and 61:
Dr. Susan Cohn with a patientProgra
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60MembersInvestigator*Douglas Bisho
Page 64 and 65:
compared to mice treated with IP ci
Page 66 and 67:
Using a structure-based rationale,
Page 68 and 69:
incorporation of other genetic elem
Page 70 and 71:
Additional Program Highlights*Resea
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Page 74 and 75:
Hart, John MD* # Dougherty U, Sehde
Page 76 and 77:
Nanda, Rita MD# Wei M, Xu J, Dignam
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# Yang C, Karczmar GS, Medved M, Ot
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Selected Major Grants and AwardsThe
Page 82 and 83:
Program 5Advanced Imaging
Page 84 and 85:
MembersInvestigator*Hiroyuki Abe MD
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in as many as 86% of the measuremen
Page 88 and 89:
investigators and engineers from co
Page 90 and 91:
have important clinical implication
Page 92 and 93:
Theme: Image-Guided TherapyCharles
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irradiated to a variety of doses ne
Page 96 and 97:
Page 98 and 99:
* Jansen SA, Fan X, Karczmar GS, Ab
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Program 6Cancer Risk and Prevention
Page 102 and 103:
MembersInvestigator*Habibul Ahsan M
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to prostate cancer. The work has ma
Page 106 and 107:
Dr. Ahsan’s team showed that sele
Page 108 and 109:
Theme: Psychological and Bio-Behavi
Page 110 and 111:
Daniel McGehee, PhDAssociate Profes
Page 112 and 113:
Sarah Gehlert, PhDProfessor of the
Page 114 and 115:
Selected New Funding•• Lisa San
Page 116 and 117:
Page 118 and 119:
Gehlert, Sarah PhD* Gehlert S, Sohm
Page 120 and 121:
Olopade, Olufunmilayo MBBS* Bradbur
Page 122 and 123:
Clinical Trials ActivityDr. Alessan
Page 124 and 125:
The clinical trials activity of the
Page 126 and 127:
Shared ResourcesDr. Vytas Bindokas
Page 128 and 129:
Biostatistics Core FacilityScientif
Page 130 and 131:
collaborations. The Facility mainta
Page 132 and 133:
The services provided include:•
Page 134 and 135:
Other Resources and Centers
Page 136 and 137:
Cancer Resource CenterThe UCCRC off
Page 138 and 139:
CECOS has successfully developed an
Page 140 and 141:
Committee on ImmunologyThe Committe
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The University of Chicago Medical C
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HighlightsThe Gwen and Jules Knapp
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Leukemia and Lymphoma Society Speci
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Institute for Genomics and Systems
Page 150 and 151:
Systems Biology Approach for the St
Page 152 and 153:
Immunology and Cancer ProgramMaria-
Page 154 and 155:
Cancer Risk and Prevention ProgramA
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www.uccrc.uchicago.eduEditor: Hoyee
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