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Patterns of abnormal LFTs and their differential diagnosis

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Investigation <strong>of</strong> <strong>abnormal</strong> <strong>LFTs</strong><br />

• Immunoglobulins<br />

– IgG - auto immune hepatitis<br />

– IgM - primary biliary cirrhosis<br />

– IgA - alcohol<br />

– All 3 - cirrhosis<br />

• Auto antibodies<br />

– ANA / ASM - auto immune hepatitis (type I)<br />

– LKM - auto immune hepatitis (type II)<br />

– AMA - primary biliary cirrhosis

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