Patterns of abnormal LFTs and their differential diagnosis

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Patterns of abnormal LFTs and their differential diagnosis

Patterns of Abnormal LFTs and their Differential Diagnosis - Virtual ...

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Chronic liver disease screen:<br />

• HBsAg<br />

• HCV Ab<br />

• Ig’s <strong>and</strong> auto antibodies<br />

• Ferritin<br />

• A1AT<br />

• ± Caeruloplasmin / copper<br />

• AFP

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Fatty liver disease - Virtual Pathology at the University of Leeds

National Liver Histopathology EQA Scheme

Presentation in pdf format - Virtual Pathology at the University of Leeds

with Judy Wyatt

National Liver Histopathology EQA Scheme

and Incomplete Septal Cirrhosis

National Liver EQA Scheme Circulation C1 Autumn 2010

How to handle liver biopsy specimens

Case histories - Virtual Pathology at the University of Leeds

National Liver Histopathology EQA Scheme

Acute Hepatitis Including Acute Liver Failure

SOPs for the Yorkshire General Histopathology EQA Scheme

Answers - Virtual Pathology at the University of Leeds

Case 1

Chronic liver disease screen: • HBsAg • HCV Ab • Ig’s <strong>and</strong> auto antibodies • Ferritin • A1AT • ± Caeruloplasmin / copper • AFP

Liver disease severity: • Biochemical – Albumin – PT – Bilirubin • Clinical – Ascites – Hepatic encephalopathy – Nutritional status

Page 1 and 2: Patterns of abnormal LFTs and their
Page 3 and 4: Tests of liver function • Synthet
Page 5 and 6: Interpretation of LFTs • AST / AL
Page 7 and 8: Interpretation of LFTs • Albumin
Page 9 and 10: Investigation of abnormal LFTs •
Page 11: Investigation of abnormal LFTs •
Page 15 and 16: Child-Pugh score for cirrhosis seve
Page 17 and 18: Caveats • Abnormal LFTs do not al
Page 19 and 20: Case 1 Liver biopsy Miss KM, 21yrs
Page 21 and 22: Case 2 Mr J D Age 49 EtOH++ Abn LFT
Page 23 and 24: Case 3 Mrs SB Age 63 Type II diabet
Page 25 and 26: Case 3 - Mrs SB • ALT 57, AST 84,
Page 27: Conclusions • Interpreting LFTs e