16.09.2015 Views

Annual Scientific Report

AReA 1 - IDIBAPS

AReA 1 - IDIBAPS

SHOW MORE
SHOW LESS
  • No tags were found...

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

INTRODUCTION<br />

IDIBAPS Platforms<br />

Biobank of Hospital Clínic-IDIBAPS<br />

www.clinicbiobanc.org<br />

The Biobank is a centralised institutional support platform for coordinating the collection, processing, storage and transfer of<br />

biological samples to promote biomedical research of the highest standard.<br />

When it was first set up, the Biobank had a dual mission:<br />

• To provide the scientific community with standard, well characterised biological samples with high added value, in order to<br />

promote, foster and develop biomedical research in accordance with current legislation.<br />

• To standardise all the Institute’s research sample collections (in accordance with article 67 of Law 14/2007, relating to Biomedical<br />

Research Act).<br />

The bank’s catalogue of samples is divided into three broad categories which are available for scientific purposes for the consolidation<br />

of personalized medicine:<br />

1) Neurological Tissue Biobank<br />

A nervous tissue repository (brain and spinal cord) created from donations from cadavers with or without neurological conditions,<br />

helping to facilitate research into neurological illnesses in order to improve diagnoses and enhance patient assistance.<br />

2) Tumour Biobank and Anatomical Pathologies Collections<br />

A Repository of tumorous tissue and samples from cancer patients. This biobank also manages an extensive collection of<br />

other disease-related tissue provided by the Department of Anatomical Pathology at the Hospital Clínic from excess samples<br />

used in their diagnoses. This material is essential to providing current large-scale tissue research projects with the samples<br />

they require.<br />

3) Blood and Fluid Biobank<br />

This repository contains samples of metabolic, inflammatory bowel, hepatic, digestive and maternal and foetal diseases,<br />

among others. It houses a large range of samples of scientific interest, primarily DNA, serum and plasma, which are provided<br />

by doctors’ surgeries and laboratories where blood and fluid are taken for lab tests and blood and fluid donation.<br />

Services<br />

The Biobank of Hospital Clínic – IDIBAPS offers a wide range of samples and services. The scientific community may make<br />

full use of the bank’s equipment and professional staff to achieve their most ambitious goals. The work of the biobank<br />

goes beyond simply providing samples; they offer support to researchers during the various stages of projects requiring the<br />

use of biological samples.<br />

Sample providing<br />

• Nerve tissue from cadaveric donors affected by neurologic diseases<br />

• Frozen biological samples and paraffin-embedded tissue blocks representing the most common tumours<br />

• DNA, serum, plasma and PBMCs from different diseases as well as from control donors<br />

Technical and scientific advice<br />

• Creation and management of new collections<br />

• Methodology (technical guidance)<br />

• Experimental design with human and animal tissue samples<br />

• Design and interpretation of immunohistochemical studies<br />

• Quality management programmes<br />

• Harmonization of quality procedures for the handling of DNA samples<br />

• Technical assessment for the manipulation of the Biobank equipment (microdissector and morphometre)<br />

36

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!