Annual Scientific Report

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INTRODUCTION Shared Platforms Proteomics Unit (IDIBAPS-UB-PCB Platform) Services • Separation of peptides and proteins • Characterisation and sequencing of peptides and proteins • Analysis of complex protein samples • Quantitative analysis of complex protein samples (DIGE, ITRAQ, LABEL-FREE LC-MS) • Whole protein analysis (top-down proteomics) Equipment • Strips Protean IPG Bio-Rad system for sorting of proteins by pl (IDIBAPS) • SDS-PAGE system for sorting of Protean Dodecacell Bio-Rad gels (IDIBAPS) • SDS-PAGE system for sorting of Mini Protean Dodecacell Bio-Rad gels (IDIBAPS) • PDQUEST Bio-Rad analysis software for 2-dimensional gels (IDIBAPS) • Scanner for digitising G-810 Bio-Rad gels (IDIBAPS) • Fluro-S Bio-Rad analyser (IDIBAPS) • Solution automatic genomic digester (IDIBAPS) • Espectròmetre de masses: MALDI-TOF-TOF 4800 (Applied Biosystems) • MALDITOF Voyager DE Prespective (IDIBAPS) • Thermo Finnigan NanoESI-Ion Trap LCQ DECA XP (IDIBAPS) • VELOS ORBITRAP-ETD NanoESI LTQ Linear Ion Trap (UB) • PROXEON LC nanoEASY (IDIBAPS) • Thermo Finnigan MicroHPLC Surveyor (IDIBAPS) • Typhoon (GE HealthCare) for quantitative analysis of proteins (UB) • Decyder; computer analysis of differential studies (UB) • Peptide and protein analytical software (SEQUEST, PROTEOME DISCOVERER, PEAKS, etc.) <strong>Scientific</strong> coordinator(s): • Dr. Oriol Bachs UB obachs@ub.edu Staff: • Dr. Josep Maria Estanyol Unit supervisor (SCT-UB) jmestanyol@ub.edu • Dr. M. José Fidalgo UB. Masses supervising technician • Dr. Eva Olmedo IDIBAPS. Technician • Mr. Juan Martínez Heredia IDIBAPS. Technician Location: • UB School of Medicine 5th floor, South Wing, Casanova, 143 44
IDIBAPS Research and Innovation Animal housing facilities (UB) Services • To comply with the applicable legislation on protecting animals used for experiments and for other scientific purposes: - Curing and maintenance of the housed species - Accreditation control of the personnel implicated in the handling of animals, according to legislation - Control of the procedures approved by the Catalan Environmental Departament. Generalitat de Catalunya • Forming part of the Animal Experimentation Ethics Committee (CEEA-UB) • Crossbreeding and maintenance of colonies of transgenic breeds, knock-out and special breeds of rat • Technical and veterinary counselling. Veterinary control • Supervision of reception and the shipment of animals to other centres Equipment • Stabling drawers and racks (FC + UB) • Ventilated racks (UB) • Extractors (UB + FC) • Biological safety chamber (UB) • Siemens X-ray equipment (FC) • Experimental large animal operating theatre (UB + FC) • Surgical lenses (UB) • Ventilators (UB + FC) • Anaesthesia equipment (UB) • Autoclaves (UB) • Equipment washer and bottle washer (UB) • SAS (UB) <strong>Scientific</strong> coordinator(s): • Dr. Jordi Alberch UB alberch@ub.edu • Dr. Jaume Bosch HC jbosch@clinic.ub.es • Dr. Josep Mª Tusell CSIC jmtnqi@iibb.csic.es Staff: • Dr. Amèrica Giménez Animal housing facilities supervisor. Senior technician (UB) agimenez@ub.edu • Mr. Josep Ma Marimon Cryopreservation and embyonic transference supervisor. Senior technician (UB) • Ms. Leire Barguín Veterinarian (UB) • Mr. David Almató Experimenter. Category III stabling technician (UB) • Ms. Dolores Ruiz Experimenter. Category III stabling technician (UB) • Ms. Blanca Caballero Keeper. Stabling assistant (FC) • Sr. David López Keeper. Stabling assistant (FC) • Mr. Ivan Ortega Experimenter. Category III stabling technician • Mr. Raul Ramírez Experimenter. Category III stabling technician • Mr. Robert Fortea Experimenter. Category III stabling technician • Cleaning personnel 1FC and 3UB Location: • 6th floor, School of Medicine (~600 sq m) 45
Page 3 and 4: Annual Scientific Report Rosselló,
Page 5: INDEX Foreword IDIBAPS • Introduc
Page 8 and 9: Presentation IDIBAPS Foreword Intro
Page 10 and 11: Organisation chart Governing Board
Page 12 and 13: INNOVATION IDIBAPS Organisation cha
Page 14 and 15: It should be mentioned that the sum
Page 16 and 17: Research resources The funding obta
Page 18 and 19: Institució Catalana de Recerca i E
Page 20 and 21: Innovation and transference With th
Page 22 and 23: Spin-off companies The knowledge de
Page 24 and 25: Impact upon clinical practice The f
Page 26 and 27: Title Associated Journal Short Text
Page 28 and 29: IDIBAPS IN FIGURES Surgical innovat
Page 30 and 31: Study of experimental surgery in la
Page 32 and 33: Abreviated Journal Name Original Ar
Page 34 and 35: Abreviated Journal Name Original Ar
Page 36 and 37: INTRODUCTION IDIBAPS Platforms Biob
Page 38 and 39: People Scientific coordinator(s): D
Page 40 and 41: Cytometry and cell sorting www.idib
Page 42 and 43: SOCIETY Functional Genomics The Gen
Page 46 and 47: SOCIETY DNA Unit (Hospital Clínic)
Page 48 and 49: SOCIETY Electronic Microscopy Unit
Page 50 and 51: NETWORKING Spanish excellence netwo
Page 52 and 53: Spanish Biomedical Research Centre
Page 54 and 55: AIDS Research Network (RIS) www.ret
Page 56 and 57: Networked Biomedical Research Suppo
Page 58 and 59: CIBER IDIBAPS Team Principal invest
Page 60 and 61: CENITS AND CONSOLIDERS CENITs and C
Page 62 and 63: NoE - Genetic and environmental ris
Page 64 and 65: TRAINING Research seminars The rese
Page 66 and 67: Author Title Doctorate thesis reade
Page 68 and 69: IDIBAPS and society This research c
Page 71 and 72: Inflammatory joint diseases 72 Syst
Page 73 and 74: AREA 1 BIOLOGICAL AGGRESSION AND RE
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AREA 1 BIOLOGICAL AGGRESSION AND RE
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Respiratory, cardiovascular, renal
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AREA 2 Respiratory, cardiovascular,
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AREA 2 Respiratory, cardiovascular
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Liver, digestive system metabolism
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AREA 3 Liver, digestive system and
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AREA 3 LIVER, DIGESTIVE SYSTEM AND
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Clinical and experimental neuroscie
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AREA 4 Clinical and experimental ne
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oncology and HAEMATOLOGY Biological
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AREA 5 Oncology and haematology Bio
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AREA 5 Oncology and haematology Hum
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AREA 5 Oncology and haematology Dia
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AREA 5 Oncology and haematology Dia
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AREA 5 Oncology and haematology Mol
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AREA 5 Oncology and haematology Gen
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AREA 5 Oncology and haematology Mel
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AREA 5 Oncology and haematology Mel
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AREA 5 Oncology and haematology Hem
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AREA 5 Oncology and haematology Phy
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AREA 5 Oncology and haematology Phy
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AREA 5 Oncology and haematology Cel
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transversal research groups Barcelo
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transversal research groups Clinica
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transversal research groups Clinica
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transversal research groups Transve
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transversal research groups Transve
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transversal research groups Researc
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Team leader index A Àlvar Agustí.
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Annual Scientific Report

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