Annual Scientific Report

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People Scientific coordinator(s): Director Dr. Joan Albert Barberà HCB jbarbera@clinic.ub.es Scientific coordinator Dr. Anna Bosch Comas IDIBAPS abosch1@clinic.ub.es Managing assistant Ms. Meritxell Rufet Fundació Clínic mrufet@clinic.ub.es Dr. Ellen Gelpí Neurologist. Senior Technician I (UB) Ms. Carina Antiga Secretary (IDIBAPS) Ms. Sara Charif Laboratory technician (IDIBAPS) Ms. Rosa Rivera Specialised technician – III (UB) Ms. Verónica Santiago Laboratory technician (CIBERNED) Mr. Abel Muñoz Autopsy Assistant (Fundació Clínic) Informed Consent Manager Ms. Ángela Martín Fundació Clínic martin3@clinic.ub.es Lab Manager Ms. Regina A. Cañaveras Fundació Clínic rcanaver@clinic.ub.es Ms. Leyre Etxarri Autopsy Assistant (Fundació Clínic) • Tumour bank Laura Gelabert Laboratory technician (Fundació Clínic) Mónica Marín Laboratory technician (Hospital Clínic) • Neurological tissue bank Dr. Francesc Graus (HC-UB) fgraus@clinic.ub.es Eva Fernández López Laboratory technician (Hospital Clínic) Raquel Bermudo Gascón Bank Manager (Fundació Clínic) • Tumour bank Dr. Pedro L. Fernández HC plfernan@clinic.ub.es • Blood and Fluid Biobank Albert Davins Laboratory technician (CIBERDEM) Roser Mas Laboratory technician and quality supervisor (IDIBAPS) • Blood and Fluid Biobank Dra. Anna Bosch Comas IDIBAPS abosch1@clinic.ub.es Anna Morales Laboratory technician (IDIBAPS) Laura Tugores Nurse (IDIBAPS) Staff: • Neurological tissue bank Dr. Maria Jesús Rey Neuropathologist. Senior technician – I (UB) Location: • Neurological tissue bank Faculty of Medicine UB. South wing, floor 0 (~140 sq m) • Tumour bank, Blood and Fluid Biobank C/ Roselló 149-153, -1 Floor 38
IDIBAPS Research and Innovation Bioinformatics The Bioinformatics Unit is mainly devoted to the analysis and support in the interpretation of data coming from OMICS disciplines. The integration of data coming from the Genomics, Proteomics, or Metabolomics fields requires huge efforts in the development of common languages, tools, and specific databases. Differential expression or classification studies in every OMICS field usually face two big challenges: the high dimensionality and the small sample size. Furthermore, clinical research is frequently aimed at understanding very complex biological problems for the discovery of specific biomarkers for diagnosis. It is then necessary to use sophisticated tools with complex statistical methodologies to derive information in the usual conditions of high-throughput experiments. At this current moment, the emerging field of Systems Biology is aimed at analyzing and integrating data from the entire OMICS field to ultimately create working models of entire biological systems. Services Bioinformatic support in different areas of biomedical research, particularly in OMICS technologies; development of new tools and diffusion: • Consultancy: counselling in experimental design; low-level and quality control analyses; orientation on biostatistical resources; assistance in tool utilisation; intensive analysis of OMICS technology data in collaborative settings; interpretation of results. • Bioinformatic resources development and administration: software processing; access to computer resources via proprietary Linux services; development of customised tools and databases, particularly in web settings. Equipment • IBM eServer BladeCenter HS21 server. 1 Intel (R) Xeon (R) E5345 @ 2.33 Ghz CPU. 64 Bit. RAM: 16 GB. H.D: 465 GB (Raid 5) OS: Suse Linux Enterprise Server 10 • Intel Dual Xeon 3.0 GHz Server. 32 Bit. RAM 3 GB. HD 120 GB. OS Linux Red Hat 9 • Intel Dual Xeon 3.0 GHz Server. 32 Bit. RAM 3 GB. HD 120 GB. OS Windows 2003 OS • HP XW4200 Server. Pentium IV 3.5 GHz. HD 120 GB. RAM 2 GB. OS Windows XP • 2 PC Intel Core 2 Duo® E8400 @3.0GHz. Arq. 32 Bits, Memoria RAM 3.5GB, HD: 250 GB. OS: Windows XP Scientific coordinator: • Dr. Susana Kalko (IDIBAPS) skalko@clinic.ub.es Staff: • Dr. Nuria Queralt Rosinach Technician (IDIBAPS) • Sr. Joan Protasio Technician (IDIBAPS) Location: • Bioinformatics Platform CEK C/ Roselló, 149-153, -1 Floor 39
Page 3 and 4: Annual Scientific Report Rosselló,
Page 5: INDEX Foreword IDIBAPS • Introduc
Page 8 and 9: Presentation IDIBAPS Foreword Intro
Page 10 and 11: Organisation chart Governing Board
Page 12 and 13: INNOVATION IDIBAPS Organisation cha
Page 14 and 15: It should be mentioned that the sum
Page 16 and 17: Research resources The funding obta
Page 18 and 19: Institució Catalana de Recerca i E
Page 20 and 21: Innovation and transference With th
Page 22 and 23: Spin-off companies The knowledge de
Page 24 and 25: Impact upon clinical practice The f
Page 26 and 27: Title Associated Journal Short Text
Page 28 and 29: IDIBAPS IN FIGURES Surgical innovat
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Page 32 and 33: Abreviated Journal Name Original Ar
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Page 36 and 37: INTRODUCTION IDIBAPS Platforms Biob
Page 40 and 41: Cytometry and cell sorting www.idib
Page 42 and 43: SOCIETY Functional Genomics The Gen
Page 44 and 45: INTRODUCTION Shared Platforms Prote
Page 46 and 47: SOCIETY DNA Unit (Hospital Clínic)
Page 48 and 49: SOCIETY Electronic Microscopy Unit
Page 50 and 51: NETWORKING Spanish excellence netwo
Page 52 and 53: Spanish Biomedical Research Centre
Page 54 and 55: AIDS Research Network (RIS) www.ret
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Page 58 and 59: CIBER IDIBAPS Team Principal invest
Page 60 and 61: CENITS AND CONSOLIDERS CENITs and C
Page 62 and 63: NoE - Genetic and environmental ris
Page 64 and 65: TRAINING Research seminars The rese
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Page 68 and 69: IDIBAPS and society This research c
Page 71 and 72: Inflammatory joint diseases 72 Syst
Page 73 and 74: AREA 1 BIOLOGICAL AGGRESSION AND RE
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AREA 1 BIOLOGICAL AGGRESSION AND RE
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Respiratory, cardiovascular, renal
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AREA 2 Respiratory, cardiovascular,
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AREA 2 Respiratory, cardiovascular
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Liver, digestive system metabolism
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AREA 3 Liver, digestive system and
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AREA 3 LIVER, DIGESTIVE SYSTEM AND
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Clinical and experimental neuroscie
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AREA 4 Clinical and experimental ne
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oncology and HAEMATOLOGY Biological
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AREA 5 Oncology and haematology Bio
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AREA 5 Oncology and haematology Hum
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AREA 5 Oncology and haematology Dia
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AREA 5 Oncology and haematology Dia
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AREA 5 Oncology and haematology Mol
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AREA 5 Oncology and haematology Gen
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AREA 5 Oncology and haematology Mel
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AREA 5 Oncology and haematology Mel
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AREA 5 Oncology and haematology Hem
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AREA 5 Oncology and haematology Phy
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AREA 5 Oncology and haematology Cel
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transversal research groups Barcelo
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transversal research groups Clinica
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transversal research groups Clinica
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transversal research groups Transve
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transversal research groups Transve
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transversal research groups Researc
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Team leader index A Àlvar Agustí.
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Annual Scientific Report

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