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Biotech financing

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US and European biotechnology IPOs by year<br />

Capital raised<br />

Number of deals<br />

8<br />

100<br />

7<br />

6<br />

75<br />

5<br />

4<br />

50<br />

3<br />

2<br />

25<br />

1<br />

0<br />

2000<br />

2001<br />

2002<br />

2003<br />

2004<br />

2005<br />

2006<br />

2007<br />

2008<br />

2009<br />

2010<br />

2011<br />

2012<br />

2013<br />

2014<br />

2015<br />

0<br />

Source: EY, Capital IQ and VentureSource.<br />

The last quarter of 2015 could point to the beginning of the end<br />

in the long-running biotech IPO boom. Still, for the year, 2015<br />

was no slouch. Seventy-eight biotechs went public in 2015,<br />

compared with 95 (the all-time record) in 2014. The 2015<br />

figure was still more than twice the annual average over the<br />

past 15 years (34) and tied 2000 for the second-most ever.<br />

<strong>Biotech</strong>s raised US$5.2 billion in these debut offerings (down<br />

22% from 2014’s US$6.7 billion), the industry’s third-highest<br />

IPO total. The average amount raised was similar to the 2014<br />

mean (US$67 million versus US$71 million), with the top<br />

spots going to oncology-focused NantKwest in the US and<br />

Adaptimmune in Europe. NantKwest’s US$238 million IPO<br />

established a record post-money valuation of US$2.6 billion,<br />

quite a feat for a company with a lead product in Phase 1.<br />

Adaptimmune’s US$191 million raise showcased investors’<br />

ongoing enthusiasm for immuno-oncology. IPOs in the US<br />

accounted for 45 of the deals, of which 34 raised US$50 million<br />

or more and 13 raised at least US$100 million.<br />

Beyond borders 2016 — <strong>Biotech</strong> <strong>financing</strong><br />

11

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