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Top European biotech IPOs, 2015<br />

Company<br />

Country<br />

Lead product<br />

clinical stage<br />

Therapeutic<br />

focus<br />

Relevant raised<br />

(US$m)<br />

Post-IPO<br />

performance (as of<br />

29 February 2016)<br />

Adaptimmune United Kingdom Phase II Oncology $191 -58%<br />

Cassiopea Italy Phase II Dermatology $172 -19%<br />

Ascendis Pharma Denmark Phase II Metabolic/Endocrinology $124 -4%<br />

Biocartis Belgium Diagnostic Diagnostic $109 8%<br />

Nabriva Therapeutics Austria Phase II Infectious disease $106 -12%<br />

Camurus Sweden Phase II Multiple $87 24%<br />

OSE Pharma International France Phase III Oncology $65 -28%<br />

Nordic Nanovector Norway Phase II Oncology $64 -60%<br />

Abivax France Marketed Infectious disease $64 -37%<br />

Cerenis Therapeutics France Phase II Cardiovascular $60 -17%<br />

Diurnal United Kingdom Phase III Metabolic/Endocrinology $57 -7%<br />

Curetis Germany Diagnostic Infectious disease $45 -14%<br />

Bone Therapeutics Belgium Phase III Musculoskeletal $41 14%<br />

Kiadis Pharma Netherlands Phase II Oncology $36 -21%<br />

Poxel France Phase II Metabolic/Endocrinology $30 24%<br />

Nuevolution Denmark Preclinical Oncology $30 -51%<br />

Strongbridge Biopharma Ireland Phase III Metabolic/Endocrinology $25 -60%<br />

Redx Pharma United Kingdom Preclinical Oncology $23 -55%<br />

Faron Pharmaceuticals Finland Phase III Respiratory $15 -8%<br />

Biophytis France Phase II Musculoskeletal $11 -8%<br />

Source: EY, Capital IQ and VentureSource.<br />

2014 and 2015 were two of Europe’s most impressive IPO years,<br />

even as the climate lagged behind that of the US. Thirty-three<br />

European companies went public in 2015 (not all of them on<br />

European exchanges, as Nabriva illustrates), down slightly<br />

from 34 in 2014. Total fundraising via IPOs was also down,<br />

from US$1.9 billion in 2014 to US$1.4 billion in 2015, as<br />

was the average amount raised (from US$56 million in 2014<br />

to US$42 million in 2015). UK immunotherapy specialist<br />

Adaptimmune topped the charts with its US$191 million IPO in<br />

May 2015, but like the majority of the top 20 European IPOs,<br />

the company’s share price had fallen as of December 31 relative<br />

to its IPO price.<br />

Beyond borders 2016 — <strong>Biotech</strong> <strong>financing</strong><br />

25

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