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2015-JNJ-Citizenship-Sustainability-Report

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Completion of<br />

Healthy Future 2015<br />

Goals<br />

Our performance against our<br />

Healthy Future 2015 goals has<br />

helped us advance global health;<br />

steward a healthy environment;<br />

increase sustainability among<br />

our suppliers; develop engaged,<br />

health-conscious and safe<br />

employees; advance community<br />

wellness; enhance outcomes<br />

measurement in philanthropy;<br />

and increase our transparency<br />

and collaborations. Progress<br />

is reported here and in more<br />

detail within our report.<br />

Advancing Global Health<br />

Goal: One research partnership and three<br />

licensing agreements finalized to address diseases<br />

of the developing world.<br />

Actual: Our efforts to reach this goal began<br />

with commitments made in 2011 as part of the<br />

London Declaration to end Neglected Tropical<br />

Diseases (NTDs) by 2020, and include working<br />

with partners, such as Drugs for Neglected<br />

Diseases initiative (DNDi), to develop a chewable<br />

formulation of VERMOX ® (mebendazole), our<br />

treatment for intestinal worms in children. In<br />

2013, the Company executed a data-sharing<br />

agreement with DNDi for preclinical research<br />

on flubendazole as a potential new treatment<br />

against parasites that cause lymphatic filariasis<br />

(elephantiasis) and onchocerciasis (river blindness);<br />

a licensing agreement with PATH on TMC278LA<br />

pre-exposure prophylaxis; and in-licensing<br />

agreements with Wellcome Trust and Ku Leuven in<br />

the field of dengue. We bolstered our portfolio of<br />

treatments against NTDs in 2015 when we added<br />

the early development program for dengue to our<br />

Global Public Health portfolio, aiming to develop<br />

in partnership with key research institutions<br />

innovations that protect against dengue for people<br />

traveling to and living in endemic areas.<br />

In 2014, Janssen Global Public Health<br />

expanded its collaboration with the International<br />

Partnership for Microbicides (IPM) to include<br />

worldwide development and commercialization of<br />

dapivirine for HIV prevention in women. In 2015,<br />

Janssen Sciences Ireland UC (Janssen), one of the<br />

pharmaceutical companies of Johnson & Johnson,<br />

expanded its relationship with IPM through a new<br />

agreement to help protect women against sexual<br />

transmission of HIV. This new agreement grants<br />

IPM an exclusive, royalty-free license to develop<br />

darunavir, an antiretroviral (ARV) medicine used for<br />

HIV-1 treatment, as a vaginal or rectal microbicide<br />

for HIV prevention in selected developing countries<br />

at an affordable cost. 2 A<br />

Goal: Ninety least-developed and middle-income<br />

countries have our HIV therapies registered and<br />

available at special-effort pricing.<br />

Actual: In more than 100 countries, our HIV<br />

medicines are made available either at specialeffort<br />

or reduced pricing, provided local regulatory<br />

systems allow import prior to registration. The<br />

90 least-developed or middle-income countries<br />

identified in our Healthy Future 2015 goal are part<br />

of an HIV Access Territory from which we measure<br />

our progress. A<br />

2. http://www.ipmglobal.org/publications/ipm-receivesworldwide-rights-hiv-prevention-medicine<br />

A<br />

Included in the scope of ERM CVS assurance engagement. Please see page 96 for their findings and conclusions.<br />

2015 Citizenship & Sustainability Report 10

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