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Laboratory news & BioScience March 2017

New Zealand's leading scientific publication for more than 20 years. This bi-monthly magazine provides the latest up to date information on new products and services to a readership which is carefully targeted and updated on a regular basis.

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NEW ZEALAND LABORATORY NEWS | NEW ZEALAND BIOSCIENCE<br />

Targeted microbiome modulation from<br />

OptiBiotix demonstrates potential to boost<br />

the health benefits of existing probiotics<br />

Research to be presented by<br />

microbiologist Stephen O’Hara,<br />

CEO of OptiBiotix Health, at the<br />

Microbiome R&D and Business<br />

Collaboration Congress: Asia in<br />

Hong Kong on the 1-2 <strong>March</strong> <strong>2017</strong><br />

will demonstrate that OptiBiotix’s<br />

microbiome modulators can<br />

increase the growth and biological<br />

effect of specific microbial species<br />

in the human microbiome.<br />

The oral presentation will show that<br />

OptiBiotix’s microbiome modulators<br />

have successfully increased the<br />

growth and biological effect of multiple<br />

species of microbe in human gut models,<br />

including their own cholesterol-reducing<br />

probiotic, LP-LDL®. By using the microbiome<br />

modulator, LPGOS, to increase the growth<br />

of LP-LDL® researchers reduced cholesterol<br />

as much as 27%.<br />

This new research from OptiBiotix demonstrates<br />

the potential for the development<br />

of species or genera-specific probiotics to<br />

selectively enhance the growth and health<br />

benefits of existing probiotics. In addition,<br />

there is the potential for microbiome modulators,<br />

which selectively modify an individual’s<br />

microbiome to improve health, to be<br />

added to a range of food products.<br />

Stephen O’Hara, CEO of OptiBiotix, commented,<br />

“The ability to create designer ingredients<br />

which can modify an individual’s<br />

microbiome to improve health is a hugely<br />

exciting development in global microbiome<br />

research and product development. I believe<br />

we are fast approaching the next stage<br />

in the development of the microbiome in<br />

healthcare, where scientists have the ability<br />

to precision engineer components of the<br />

microbiome to prevent, manage and treat<br />

many of today’s chronic lifestyle diseases.”<br />

The human microbiome<br />

The human digestive tract contains a<br />

complex and diverse ecosystem of trillions<br />

of bacteria. Recently, advances in molecular<br />

and analytical techniques (metagenomics,<br />

metabolomics) have permitted identification<br />

and quantitation of species and<br />

strains of bacteria that inhabit the gastrointestinal<br />

tract, their metabolic activity, and<br />

interactions with the human host. These<br />

studies have provided greater insight into<br />

the role of gut and their metabolites in<br />

health and disease.<br />

NIH https://commonfund.nih.gov/hmp/<br />

index<br />

Web MD http://www.webmd.com/digestive-disorders/what-your-gut-bacteriasay-your-health#1<br />

About OptiBiotix<br />

OptiBiotix was formed in <strong>March</strong> 2012<br />

by Stephen O’Hara to develop compounds<br />

which modify the human microbiome –<br />

the collective genome of the microbes in<br />

the body – to prevent and manage human<br />

disease.<br />

VOL. 26 NO. 1 | MARCH <strong>2017</strong><br />

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Advanced Microscopy Systems | Dr Rob Woolley | Ph: (021) 288 8636<br />

sales@coherent.com.au | www.coherent.com.au<br />

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