Laboratory news & BioScience March 2017
New Zealand's leading scientific publication for more than 20 years. This bi-monthly magazine provides the latest up to date information on new products and services to a readership which is carefully targeted and updated on a regular basis.
New Zealand's leading scientific publication for more than 20 years. This bi-monthly magazine provides the latest up to date information on new products and services to a readership which is carefully targeted and updated on a regular basis.
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NEW ZEALAND LABORATORY NEWS | NEW ZEALAND BIOSCIENCE<br />
Targeted microbiome modulation from<br />
OptiBiotix demonstrates potential to boost<br />
the health benefits of existing probiotics<br />
Research to be presented by<br />
microbiologist Stephen O’Hara,<br />
CEO of OptiBiotix Health, at the<br />
Microbiome R&D and Business<br />
Collaboration Congress: Asia in<br />
Hong Kong on the 1-2 <strong>March</strong> <strong>2017</strong><br />
will demonstrate that OptiBiotix’s<br />
microbiome modulators can<br />
increase the growth and biological<br />
effect of specific microbial species<br />
in the human microbiome.<br />
The oral presentation will show that<br />
OptiBiotix’s microbiome modulators<br />
have successfully increased the<br />
growth and biological effect of multiple<br />
species of microbe in human gut models,<br />
including their own cholesterol-reducing<br />
probiotic, LP-LDL®. By using the microbiome<br />
modulator, LPGOS, to increase the growth<br />
of LP-LDL® researchers reduced cholesterol<br />
as much as 27%.<br />
This new research from OptiBiotix demonstrates<br />
the potential for the development<br />
of species or genera-specific probiotics to<br />
selectively enhance the growth and health<br />
benefits of existing probiotics. In addition,<br />
there is the potential for microbiome modulators,<br />
which selectively modify an individual’s<br />
microbiome to improve health, to be<br />
added to a range of food products.<br />
Stephen O’Hara, CEO of OptiBiotix, commented,<br />
“The ability to create designer ingredients<br />
which can modify an individual’s<br />
microbiome to improve health is a hugely<br />
exciting development in global microbiome<br />
research and product development. I believe<br />
we are fast approaching the next stage<br />
in the development of the microbiome in<br />
healthcare, where scientists have the ability<br />
to precision engineer components of the<br />
microbiome to prevent, manage and treat<br />
many of today’s chronic lifestyle diseases.”<br />
The human microbiome<br />
The human digestive tract contains a<br />
complex and diverse ecosystem of trillions<br />
of bacteria. Recently, advances in molecular<br />
and analytical techniques (metagenomics,<br />
metabolomics) have permitted identification<br />
and quantitation of species and<br />
strains of bacteria that inhabit the gastrointestinal<br />
tract, their metabolic activity, and<br />
interactions with the human host. These<br />
studies have provided greater insight into<br />
the role of gut and their metabolites in<br />
health and disease.<br />
NIH https://commonfund.nih.gov/hmp/<br />
index<br />
Web MD http://www.webmd.com/digestive-disorders/what-your-gut-bacteriasay-your-health#1<br />
About OptiBiotix<br />
OptiBiotix was formed in <strong>March</strong> 2012<br />
by Stephen O’Hara to develop compounds<br />
which modify the human microbiome –<br />
the collective genome of the microbes in<br />
the body – to prevent and manage human<br />
disease.<br />
VOL. 26 NO. 1 | MARCH <strong>2017</strong><br />
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