CosBeauty Magazine #78

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Feature Could this be the fountain of youth? Scientists have discovered new drugs that could slow down the ageing process and potentially extend lifespan. Words by erin docherty 98 www.cosbeauty.com.au
Beauty There’s no doubt that research into ageing and extending the lifespan of humans and animals, has become a serious endeavor. And it seems we are slowly unlocking the mystery of how to reverse the ageing process. Often referred to as the ‘eternal fountain of youth’ ageing research is now seeking to not only tackle individual diseases, but rather treat all the diseases the arise in old age, all at once. New research is proving that slowing down the degenerative process of ageing may be closer than we think. Out with the old Scientists have recently discovered three new agents that aim to delay ageing by targeting certain cells – called senescent cells. Senescent cells are a type of cell that contributes to frailty and other age related conditions. This anti ageing strategy is called senolysis: that is, killing off old and damaged or ‘senescent’ cells. These cells take up space, grow larger, and release substances that cause inflammation. Published in the online journal Ageing, the researchers revealed that the death of senescent cells might not only promote a longer life, but also reduce illnesses associated with age. It was found that when mice were genetically engineered so that it is possible to kill of senescent cells, health drastically improved and their lifespans increased between 17 per cent and 35 per cent. The breakthrough highlights senescence as not only a key in the biological basis of ageing, but also in the prevention of health problems such as cancers and kidney problems. The researchers note that although the immune system clears the senescent cells on a regular basis, this mechanism gradually becomes less effective as we age. There’s no doubt that this research opens a new front in an already multi-pronged war against ageing. If the study passes clinical trials and proves translatable to humans, the prospects are exciting and could have a profound impact on our health. DNA changes Our DNA changes as we get older. For example, structures that cap the ends of our chromosomes (which carry our genes) called telomeres shorten with old age or stress. This results in physiological changes in the body, which increases the risk of the major conditions and diseases of ageing: cardiovascular disease, diabetes, cancer, a weakened immune system and more. New research is proving that slowing down the degenerative process of ageing may be closer than we think Professor Elizabeth Blackburn from Tasmania shared the 2009 Nobel Prize for medicine for her research on telomeres. She discovered that the telomerase enzyme can add DNA to the ends of chromosomes to slow, prevent and partially reverse the shortening of our telomeres which contributes to ageing and disease. Professor Blackburn proved that to lengthen telomeres (or stop them shortening) improving lifestyle by managing chronic stress, exercising, eating better and getting enough sleep, could lead to long-term habits that make a difference. In another anti-ageing strategy, researchers from the University of New South Wales in Australia discovered a vitamin called nictotinamide mononucleotide (NMN) that helps repair DNA damage. The researchers treated mice with NMN, finding it caused an improvement in their cells ability to repair DNA damage caused by radiation exposure or old age. After just one week of treatment the researches noted that the cells of the old mice were indistinguishable from the younger mice. What’s more is that the research won NASA’s iTech competition, because of its potential use in the planned 2025 mission to Mars. Yep, wow. On short missions, astronauts experience accelerated ageing from cosmic radiation, suffering from muscle weakness, memory loss and other symptoms when they return. On a trip to Mars, five per cent of the astronauts’ cells would die and their chances of cancer would approach 100 per cent. It’s hoped this vitamin might be able to reverse that damage. Back on earth the researchers believe NMN could also help every human defy the ageing process and stay healthy and it has potential to overcome the side effects of cancer radiotherapy and chemotherapy, especially with children. Although these drugs haven’t reached the market just yet, they nevertheless offer a glimpse into the remarkable possibilities that lie ahead for the treatment of underlying ageing and potentially a whole range of ageing conditions. CBM www.cosbeauty.com.au 99
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COSBEAUTY lifestyle health & beauty
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Researched by biochemists. Formulat
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SKINCARE REVOLUTION DEVELOPED WITH
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Contents BEAUTY regulars 12 Editor
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CONTENTS SKIN 56 The new beauty pro
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From the Editor W elcome to the sum
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@cosbeauty Beauty insider THE WHO
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I can’t think of any better repre
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Beauty Step up your makeup With the
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1. 2. Correct & conceal Use a colou
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Feature Eyes on the prize An easy w
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Beauty Lash out! Party up with fake
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hile we often find ourselves focusi
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4. Manage stress Stress seems to be
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Feature Vedic Meditation teacher A.
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Feature we grow stronger. With medi
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Beauty o makeup, no problem! Eyelas
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11. Beauty 12. 7. Napoleon Perdis M
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Feature on Nfixers surgical face Th
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Feature Nonsurgical skin tightening
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Feature Skin needling Skin needling
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Feature IPL is most commonly used f
Page 47 and 48: Enhancing what nature has given you
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Page 51 and 52: NEED TO FIND A TRUSTED PRACTITIONER
Page 53 and 54: The latest innovation in IPL The la
Page 55 and 56: Enhancement ‘Older clients are dr
Page 57 and 58: Skin ON OUR RADAR RHA MICELLAR SOLU
Page 59 and 60: Skin A foundation that was original
Page 61 and 62: Beauty Nanotechnology has revolutio
Page 63 and 64: www.cosbeauty.com.au 63
Page 65 and 66: What is SPF? Sunscreens are merely
Page 67 and 68: 14. 16. 19. 20. 22. 23. 24. 13. 21.
Page 69 and 70: Skin Introducing MEDKI8’S PHYSICA
Page 72 and 73: CELEBRITY BUTTS SO, WHAT’S INVOLV
Page 74 and 75: The MonaLisa Effect 74 www.cosbeaut
Page 76 and 77: Enhancement Spotlight on sexual dys
Page 78 and 79: The Australian Centre for Female Pe
Page 80 and 81: Enhancement LIDS BY DESIGN INTRODUC
Page 82 and 83: Feature 82 www.cosbeauty.com.au
Page 84 and 85: Beauty 1 3 2 4 12 5 11 6 8 7 10 9 2
Page 86 and 87: Beauty 1 2 3 4 5 6 9 7 8 10 11 86 w
Page 88 and 89: Stocking stuffers Good things come
Page 90 and 91: 10 makeup hacks every girl should k
Page 92 and 93: Feature Is your SKINCARE delivering
Page 94 and 95: Skin developing transdermal vehicle
Page 96 and 97: Feature How to choose the right fra
Page 100 and 101: Feature 100 www.cosbeauty.com.au
Page 102 and 103: Feature 2. Meet mountain gorillas i
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Page 106 and 107: Feature 7. Climb Kilimanjaro in Tan
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Page 110 and 111: B eauty 1. ENVIRON Tri-Peptide Comp
Page 112: Exclusively distributed in AUS & NZ
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CosBeauty Magazine #78

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