Robert S. Mittler - Department of Surgery - Emory University

32. Winberg, G., Grosmaire, L.S., Klussman, K., Hayden, M.S., Fell, H.P., Ledbetter, J.A.,
and Mittler, R.S. (1996). Surface Expression of CD28 Single Chain Fv for
Costimulation by Tumor Cells. Immunol. Rev. 153:209.
33. Brown, TJ, Shuford, WW, Wang, WC, Nadler, SG, Bailey, TS, Marquardt, H., and
Mittler RS. (1996). Characterization of a CD43/leukosialin-mediated pathway for
inducing apoptosis in human T-lymphoblastoid cells. J. Biol. Chem. 271:27686.
34. Gilliland, L.K., Norris, N.A., Marquardt, J., Tsu, T.T., Hayden, M.S., Neubauer, M.G.,
Yelton, D.E., Mittler, R.S., and Ledbetter, J.A. (1996). Rapid and Reliable Cloning of
Antibody Variable Regions and Generation of Recombinant Single Chain Antibody
Fragments. Tissue Antigens. 47:1.
35. Cabrian K.M., Berry, K.K., Shuford, W.W., Mittler, R.S., Rodgers, J.N., and Linsley,
P.S. (1996). Suppression of T Cell Dependent Immune Responses in Monkeys by
CTLA4-Ig. Transplantation Proceedings. 28:3261.
36. Hayden, M.S., Grosmaire, L.S., Norris, N.A., Gilliland, L.K.., Winberg, G., Tritchler, D.,
Tsu, T.T., Linsley, P.S., Mittler, R.S., Senter, P.D., Fell, H.P., and Ledbetter, J.A.
(1996). Costimulation by CD28 sFv Expressed on the Tumor Cell Surface or as a
Bispecific Molecule Targeted to the L6 Carcinoma Antigen. Tissue Antigens. 48:242.
37. Ledbetter J.A., Francisco, J.A., Siegall, C.B., Guilliland, L.K., Hollenbaugh, D., Aruffo,
A., Siadak, A.W., Mischel-Petty, N., Grosmaire, L.S., Gordon, M.L., Brown, T.J., Moran-
Davis, P., Mittler, R.S., Kiener, P.A., and Nadler, S.G. (1997). Agonistic activity of a
CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5. Crit.
Rev. Immunol. 17:427.
38. Melero, I., Shuford, W.W., Newby S.A., Aruffo, A., Ledbetter, J.A., Hellstrom, K.E.,
Mittler, R.S., and Chen, L. (1997). Induction of Tumor-Specific CTL and Eradication of
Established Poorly Immunogenic Tumors by Anti-4-1 BB Monoclonal Antibodies. Nat.
Med. 3:683. (Mittler and Chen are senior coauthors).
39. Shuford, W.W., Klussman, K., Tritchler, T.S., Loo, D.T., Chalupny, N.J., Siadak, A.W.,
Brown, T.J., Emswiler, J., Raecho, J., Larson, C.P., Pearson, T.C., Ledbetter, J.A.,
Aruffo, A., and Mittler, R.S. (1997). 4-1BB Costimulatory Signals Preferentially Induce
CD8 + T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell
Responses. J. Exp. Med. 186:47.
40. Loo, D.T., Chalupny, N.J., Bajorath, J., Shuford, W.W., Mittler, R.S., and Aruffo, A.
(1997). Analysis of 4-1BBL and Laminin Binding to Murine 4-1BB, a Member of the
Tumor Necrosis Factor Receptor Superfamily, and Comparison with Human 4-1BB. J.
Biol. Chem. 272:64489.
41. Melero, I., Bach, N., Hellstrom, K.E., Aruffo, A., Mittler, R.S., and Chen, L. (1998).
Amplification of Tumor Immunity by Gene Transfer of the Costimulatory 4-1BB Ligand:
Synergy with the CD28 Costimulatory Pathway. Eur. J. Immunol. 28:1116.
42. Orlikowsky, T., Wang, Z.-Q., Dudhane, A., Mittler, R.S., Trejo, V., Dannecker, G.E.,
Niethammer, D., and Hoffmann, M.K. (1998). Elevated Major Histocompatibility
Complex Class I Expression Protects T Cells From Antibody and Macrophage-Mediated
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