CV_Stefan Borgwardt - Universitäre Psychiatrische Kliniken Basel

Name Stefan Borgwardt
Akademischer Titel Prof. Dr. med.
Akademische Stellung Extraordinarius für Neuropsychiatrie
Klinische Position Leitender Arzt
Spezialisierung Psychiatrie und Psychotherapie
Forschungsinteressen: Strukturelle und funktionelle Bildgebung neuropsychiatrischer
Störungen, neurokognitive und genetische
Grundlagen der Schizophrenie, neurobiologische
Grundlagen des Psychoserisikos, neurofunktionelle
Effekte von Cannabinoiden und Heroin, Brain-Gut
Interactions.
Vorherige Tätigkeiten: Research Fellow, Institute of Psychiatry, King´s College
London, UK
Wichtigste Publikationen:
Bendfeldt K, Hofstetter L, Kuster P, Traud S, Müller-Lenke N, Naegelin Y, Kappos
L, Gass A, Nichols TE, Barkhof F, Vrenken H, Roosendaal S, Geurts JJG, Radue EW,
Borgwardt SJ (2011) Two-site 1.5T voxel-based morphometry analysis of
longitudinal gray matter changes in multiple sclerosis - Differential and overall
disease-related effects. Human Brain Mapping, in press.
Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton M, Barale F, Caverzasi E,
McGuire P (2011) Predicting psychosis: a meta-analysis of evidence. Archives of
General Psychiatry, in press.
Mechelli A, Riecher-Rössler A, Meisenzahl EM, Tognin S, Wood SJ, Borgwardt SJ,
Koutsouleris N, Yung AR, Stone JM, Phillips LJ, McGorry PD, Valli I, Velakoulis D,
Woolley J, Pantelis C, McGuire P (2011) Neuroanatomical abnormalities that
predate the onset of psychosis: a multi-centre study. Archives of General
Psychiatry 68(5):489-95.
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Fusar-Poli P, Borgwardt S, Crescini A, D’Este G, Kempton M, Lawrie S, McGuire P,
Sacchetti E (2011) Neuroanatomy of vulnerability to psychosis: A voxel-based
meta-analysis. Neuroscience and Biobehavioral Reviews, 35: 1175-1185.
Smieskova R, Allen P, Simon A, Aston J, Bendfeldt K, Drewe J, Gruber K,
Gschwandtner G, Klarhoefer M, Lenz C, Scheffler K, Stieglitz RD, McGuire P,
Riecher-Rössler A, Borgwardt SJ (2011) Different duration of at-risk mental state
associated with neurofunctional abnormalities – A multimodal imaging study.
Human Brain Mapping, published online 16 September DOI: 10.1002/hbm.21360.
Bhattacharyya S, Crippa JA, Allen P, Martin-Santos R, Borgwardt S Fusar-Poli P,
Rubia K, Joseph Kambeitz, O’ Carroll CM, Seal M, Giampietro V, Brammer M,
Zuardi AW, Atakan Z, McGuire PK (2011) Delta-9-Tetrahydrocannabinol
modulates hippocampal and striatal function during salience processing. Archives
of General Psychiatry, in press.
Fusar-Poli P, Radua J, McGuire P, Borgwardt S (2011) Neuroanatomical maps of
psychosis onset: voxelwise meta-analysis of antipsychotic-naïve VBM studies.
Schizophrenia Bulletin, in press.
Koutsouleris N, Borgwardt S, Meisenzahl EM, Bottlender R, Möller H, Riecher-
Rössler A (2011) Disease prediction in the at-risk mental state for psychosis using
neuroanatomical biomarkers: results from the FePsy-study. Schizophrenia
Bulletin, in press.
Smieskova R, Fusar-Poli P, Aston J, Simon A, Bendfeldt K, Lenz C, Stieglitz RD,
McGuire P, Riecher-Rössler A, Borgwardt SJ (2011) Insular volume abnormalities
associated with different transition probabilities to psychosis. Psychological
Medicine, in press.
Borgwardt SJ, Picchioni MM, Ettinger U, Toulopoulou T, Murray R, McGuire PK
(2010) Regional gray matter volume in monozygotic twins concordant and
discordant for schizophrenia. Biological Psychiatry, 67:956-965.
Smieskova R, Fusar-Poli P, Allen P, Bendfeldt K, Stieglitz RD, Drewe J, Radue EW,
McGuire PK, Riecher-Rössler A, Borgwardt SJ (2010) Neuroimaging predictors of
transition to psychosis – A systematic review and meta-analysis. Neuroscience
and Biobehavioral Reviews 34(8):1207-1222.
Bendfeldt K, Blumhagen JO, Egger H, Loetscher P, Dernier N, Kuster P, Traud S,
Mueller-Lenke N, Naegelin Y, Gass A, Hirsch J, Kappos L, Nichols TE, Radue EW,
Borgwardt SJ (2010) Spatiotemporal distribution pattern of white matter lesion
volumes and their association with regional gray matter volume reductions in
relapsing-remitting multiple sclerosis. Human Brain Mapping 31(10):1542-55.
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Smieskova R, Fusar-Poli P, Allen P, Bendfeldt K, Stieglitz RD, Drewe J, Radue EW,
McGuire PK, Riecher A, Borgwardt SJ (2009) The Effects of Antipsychotics on the
Brain: What Have We Learnt from Structural Imaging of Schizophrenia? – A
Systematic Review. Current Pharmaceutical Design 15: 2535-2549.
Bendfeldt K, Kuster P, Traud S, Egger H, Winklhofer S, Mueller-Lenke N, Naegelin
Y, Gass A, Kappos L, Matthews PM, Nichols TE, Radue EW, Borgwardt SJ (2009)
Association of regional gray matter volume loss and progression of white matter
lesions in multiple sclerosis – A longitudinal voxel-based morphometry study.
Neuroimage 45:60-67.
Fusar-Poli P, Crippa JA, Bhattacharyya S, Borgwardt SJ, Allen P, Martin-Santos R,
Seal M, Surguladzne SA, O’Carrol C, Atakan Z, Zuardi AW, McGuire PK (2009)
Distinct effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on neural
activation during emotional processing. Archives of General Psychiatry 66:95-105.
Haller S, Borgwardt S, Schindler C, Aston J, Radue EW, Riecher-Roessler A (2009)
Can Cortical Thickness Asymmetry Analysis Contribute to Detection of ‘At Risk
Mental State’ and ‘First Episode Psychosis’? A Pilot Study. Radiology 250:212-
221.
Bhattacharyya S, Fusar-Poli P, Borgwardt S, Martin-Santos R, Nosarti C, O’Carroll
C, Allen P, Seal M, Crippa JA, Giampietro V, Mechelli A, Atakan Z, McGuire PK
(2009) Delta-9-Tetrahydrocannabinol modulates temporal and striatal function in
humans: A neural basis for the effects of cannabis on learning and psychosis. Fulllength
article. Archives of General Psychiatry, 66(4):442-451.
Riecher-Rössler A, Aston J, Borgwardt SJ, Brewer WJ, Gschwandtner U, Pflüger M,
Stieglitz RD. Efficacy of utilising cognitive status in predicting psychosis: a 7-year
follow-up. Biological Psychiatry, 66:1023-1030.
Borgwardt SJ, Allen P, Bhattacharyya S, Fusar-Poli P, Crippa JA, Seal ML, Fraccaro
V, Atakan Z, Martin-Santos R, O’Carroll C, Rubia K, McGuire PK (2008) Neural
basis of Δ-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD): Effects during
response inhibition. Biological Psychiatry 64 (11): 966-973.
Borgwardt SJ, McGuire P, Aston J, Gschwandtner U, Pflueger M, Stieglitz RD,
Radue EW, Riecher-Rössler A (2008) Reductions in frontal, temporal and parietal
volume associated with the onset of psychsis. Schizophrenia Research 106(2-3):
20-26.
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Borgwardt SJ, Riecher-Rössler A, Dazzan P, Chitnis X, Aston J, Drewe M,
Gschwandtner U, Haller S, Pflüger M, Rechsteiner E, Semenin V, Stieglitz RD,
Radü EW, McGuire PK (2007) Regional grey matter abnormalities in the At Risk
Mental State. Biological Psychiatry 15; 61:1148-56.
Borgwardt SJ, McGuire PK, Aston J, Berger G, Dazzan P, Gschwandtner U, Pflüger
M, Radü EW, Riecher-Rössler A (2007) Structural brain abnormalities in
individuals with an At Risk Mental State who later develop psychosis. British
Journal of Psychiatry, 191(S51): 69-75.
Fusar-Poli P, Perez J, Broome M, Borgwardt SJ, Placentino A, Caverzasi E, Cortesi
M, Veggiotti P, Politi P, McGuire P (2007) Neurofunctional correlates of
vulnerability to psychosis: a systematic review and meta-analysis. Neuroscience
and Biobehavioral Reviews 31:465-84. IF: 8,2.
Fusar-Poli P, Borgwardt SJ, McGuire PK (2011) Vulnerability to psychosis: from
psychopathology to neurosciences. Maudsley Monograph. Psychology Press,
Routledge, London.
Adresse
Universitäre Psychiatrische Kliniken Basel
Psychiatrische Universitätspoliklinik
Allgemeine Psychiatrie ambulant
c/o Universitätsspital Basel
Petersgraben 4
CH-4031 Basel
Telefon: 061 265 50 40
E-Mail stefan.borgwardt@upkbs.ch
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