3DModels_for_EVs_Munich_2019_v2_IN

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Emerging diversity of extracellular vesicles EV Exosomes 50-150 nm Microvesicles 120-500 nm Large Oncosomes 500-800 nm Apoptotic Bodies 0.5-4 µm 8 · April 4, <strong>2019</strong>
Biogenesis of extracellular vesicles: microvesicles and exosomes exosomes microvesicles Van Niel and Raposo, Nature Review 2017 9 · April 4, <strong>2019</strong>
Page 1 and 2: Studying Intercellular Communicatio
Page 3 and 4: Tumor releases into microenvironmen
Page 5 and 6: Publications frequency of studies i
Page 7: Versatile EV functions in cancer Ko
Page 11 and 12: The need of physiological in vitro
Page 13 and 14: Application of 3DCoSeedis TM to pro
Page 15 and 16: Application of 3DCoSeedis TM to pro
Page 17 and 18: Comparative analysis of different E
Page 19 and 20: EV populations produced under 2D an
Page 21 and 22: qNano measurements of EV120 Optipre
Page 23 and 24: To sum up ‣ The 3DCoSeedis TM are
Page 25 and 26: Studying breast cancer small EVs Ce
Page 27 and 28: Establishment of the 3D culture for
Page 29 and 30: Establishment of the 3D culture for
Page 31 and 32: Immunohistochemistry of breast canc
Page 33 and 34: Breast cancer cells produce higher
Page 35 and 36: To sum up ‣ The 3DCoSeedis TM are
Page 37 and 38: Cell spheroids and aggregates grow
Page 39 and 40: Overall up-regulation of miRNAs and
Page 41 and 42: 41 · April 4, 2019 ARF6 signaling
Page 43 and 44: Network integrated analysis reveale
Page 45 and 46: Network integrated analysis reveale
Page 47 and 48: Conclusions ‣ 3DCoSeedsis TM are
Page 49 and 50: 49 · April 4, 2019 Thery et al., J
Page 51: Exosomes and Tumor Biology Group Ou

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